Possible Mechanisms Involved in the Cooccurrence of Oral Lichen Planus and Hashimoto's Thyroiditis

[helvella]

A quick search found about 50 posts here about Oral Lichen Planus:

healthunlocked.com/search/p...

(There are probably many more mentions as the search doesn't look at whole threads.)

Recognition of an association is at least a step. The specific recommendation to test for thyroid disease/Hashimoto's in cases of Oral Lichen Planus seems sensible - but probably far too late for most of the people who are reading here.

Mediators Inflamm. 2020; 2020: 6309238.

Published online 2020 Feb 4. doi: 10.1155/2020/6309238

PMCID: PMC7024099

Possible Mechanisms Involved in the Cooccurrence of Oral Lichen Planus and Hashimoto's Thyroiditis

Peiyao Wu, Shuhan Luo, Tao Zhou, Rui Wang, Xuemei Qiu, Peiyang Yuan, Yuqing Yang, Qi Han,

and Lu Jiang

Author information Article notes Copyright and License information Disclaimer

Go to:

Abstract

Oral lichen planus (OLP) is a chronic inflammatory oral mucosal disorder mediated by T cells, with a multifactorial etiology. Hashimoto's thyroiditis (HT) is a common autoimmune disease characterized by hypothyroidism. Although many clinical studies conducted over the past several decades have reported the cooccurrence of OLP and HT, the underlying mechanism remains unclear. This review summarizes potential mechanisms that might be involved in the cooccurrence of OLP and HT. We find that OLP and HT share a common or overlapping pathogenesis in terms of immune, heredity, environmental, and hormonal factors, which might cause cooccurrence. Furthermore, considering the latency of HT, a routine screen for thyroid diseases, particularly HT, is suggested for confirmed OLP patients.

Full paper freely available here:

ncbi.nlm.nih.gov/pmc/articl...

[Caroline888]

Hi helvella

I am one of the many with oral lichen planus and Hashimoto’s. I have always considered lichen planus to be an autoimmune disease so I guess that makes us hypos more susceptible. I have had oral lichen planus for around ten years and although only diagnosed with Hashimoto’s in 2017, I think I’ve had it very much longer than that, based on a specific symptom arising twenty-four years ago that I experienced daily and which resolved completely when on levo.

I guess it could also happen the other way around: first OLP and then Hashimoto’s.

Very interesting article. Thank you for posting.

Best wishes

Caroline