D3 16.9 on 50,000 loading dose feel awful. - Thyroid UK

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D3 16.9 on 50,000 loading dose feel awful.

Sheila46 profile image
8 Replies

I have hypothyroidism and have just be diagnosed with very low D3 and prescribed 6 week loading dose of D3 @ 50,000 weekly have only taken one so far and feel awful. I didn’t realise that on the day of the blood test I had an infection (following day was in hospital overnight being treated for this). My question is could the blood test result be inaccurate due to this infection or could it just be wrong. I am overall fit and healthy with a good diet and spend a lot of time outdoors and have no symptoms of low D3.

I would really appreciate any thoughts on this.

Thank you

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Sheila46
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humanbean profile image
humanbean

It is unlikely that an infection could change your vitamin D3 result directly. Your body might perhaps use up D3 more quickly because of an infection, but I'm only guessing and don't know for certain.

One thing I will point out is that there is a relationship between magnesium and vitamin D3 in the body, and in order to make use of D3 the body needs sufficient magnesium.

Please take a magnesium supplement but no vitamin D3 for a couple of weeks then add the vitamin D3 supplements back. Keep taking the magnesium.

The dose of magnesium you need is roughly 300mg - 400mg per day. It can be supplemented in many ways. See these links and choose a supplement that appeals to you :

drjockers.com/best-magnesiu...

naturalnews.com/046401_magn...

Three things to consider :

1) Some forms of magnesium supplement are relaxing and people find it helpful to take them in the evening before bed.

2) In order to take magnesium supplementation you need to have functioning kidneys. You can't take magnesium supplements safely if you have severe kidney disease. In that situation you would need to be monitored by a doctor before taking magnesium.

3) Magnesium is needed throughout the body. Only about 1% of the body's magnesium is found in the blood stream, and if the amount runs short in the blood stream then it gets "stolen" from other cells to keep the levels of magnesium in blood stable. So, you could have a good result from a blood test and still be severely deficient. So - don't bother testing it. The result is not informative. As long as your kidneys work well enough they will excrete excess magnesium if there is any.

Sheila46 profile image
Sheila46 in reply to humanbean

Thank you for your reply humanbean very informative. The blood tests I had done in hospital did flag up slightly low magnesium (the blood tests at the GPS’s didn’t test for this, you would think it would be automatic if there is a D3 problem ummm....) so I will do as you suggest as it makes sense .

SeasideSusie profile image
SeasideSusieRemembering in reply to Sheila46

Sheila46

The blood tests I had done in hospital did flag up slightly low magnesium (the blood tests at the GPS’s didn’t test for this, you would think it would be automatic if there is a D3 problem ummm....)

Magnesium tests are unreliable. About 99% of magnesium is stored in bone, muscles and soft tissues, leaving about 1% in the blood. So testing what's in the blood isn't giving an accurate picture of our magnesium status.

If you want to read the science, this information is from this article:

ncbi.nlm.nih.gov/pmc/articl...

Also, when established on magnesium and a couple of weeks after reintroducing D3, consider introducing another important cofactor of D3 - Vit K2-MK7 (your doctor wont know anything about this). D3 aids absorption of calcium from food and Vit K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems such as hardening of the arteries, kidney stones, etc.

D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds if taking D3 as tablets/capsules/softgels, no necessity if using an oral spray.

If you are on any blood thinning medication, do some research about Vit K2. Some articles say you shouldn't take it when on blood thinning medication but other articles say it is Vit K1 that should be avoided when on blood thinning medication.

Magnesium

and D3 need to be taken 4 hours away from thyroid medication.

D3 and Vit K2 are fat soluble so needs to be taken with some dietary fat (eg fattiest meal of the day, full fat yogurt, chunk of cheese, etc.

Sheila46 profile image
Sheila46 in reply to SeasideSusie

Thank you SeasideSusie I have looked at the article and will get K2 MK7 as you suggest. I am hoping that the magnesium will help with the on going nausea I have had since early Nov as I am getting desperate to find the answer. Waiting for an endoscopy now after a round of PPI’s for gastritis.

Marz profile image
Marz

I have read an article somewhere that daily dosing of VitD is better for some than weekly. VitD is fat soluble so best taken with a good fat in a meal. Some gel capsules contain olive oil .

Sheila46 profile image
Sheila46 in reply to Marz

Thank you Mark.

Marz profile image
Marz in reply to Sheila46

I don't think z is so close to k on the keyboard ? 🤔

Sheila46 profile image
Sheila46 in reply to Marz

Whoops sorry Marz. My spellchecker doesn’t like the z so keeps turning it back to k.

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