Review paper by Bianco now out in full

[diogenes]

I indicated earlier that this paper would come out in full in Frontiers in Thyroid Endocrinology. It is now here complete:

Front. Endocrinol., 09 July 2019 | doi.org/10.3389/fendo.2019....

The Swinging Pendulum in Treatment for Hypothyroidism: From (and Toward?) Combination Therapy

Elizabeth A. McAninch and Antonio C. Bianco

It iis downloadable. Bianco has worked very hard indeed in avoiding any meaningful reference to any of our work. There is an agenda here, which isn't in the realm of scientific honesty, but more in the business of trying to create a monopoly of thinking to a person's own benefit. He is determined that he will get the primary credit for any changes in diagnosis/therapy and the US researchers and commentators will back him.

[sy28]

Do NICE consider evidence presented in US review papers? If so, is it too late to present this while their draft guidance is under review? ...

[diogenes Remembering in reply to sy28]

I've sent it to Lyn Mynott and she can forward on to NICE.

[sy28 in reply to diogenes]

Excellent ... and your own recent paper has gone foward?

[diogenes Remembering in reply to sy28]

Believe so.

[Hidden]

Interesting.

I certainly do better on T4 + T3 than T4 alone and can imagine that I'm not the only one.

I don't understand why the NHS is so fixated on Levothyroxine only, and not allowing anything else - they've got a 'thing' about the thyroid. For other conditions it's different, e.g for high blood pressure they offer a wide variety of medicines.

I wonder what their view of prescribing T3 would be if there were more men with hypothyroidism than women...

[Hillwoman in reply to Hidden]

I wonder what their view of prescribing T3 would be if there were more men with hypothyroidism than women...

I plan to post on this very subject in a few weeks.

First though, I have to complete some reading on women's healthcare amid my own health issues and other distractions.

[Greekchick in reply to Hillwoman]

Hi Hillwoman,

This has been documented in the medical literature, particularly in the treatment of heart disease. You will find a great deal of work on this topic and I look forward to reading what you will post. All the best and good luck with your project - and your health first and foremost.

[Hillwoman in reply to Greekchick]

Thanks, Greekchick.

[humanbean in reply to Hidden]

I remember reading a few years ago that there were 85 drugs listed in the British National Formulary for the treatment of some facet of diabetes of various types. The 85 figure is out of date now - it's a bit lower - but over the last few years the number of treatments for hypothyroidism hasn't changed. There are two treatments, theoretically, but only one that most people can actually access via the NHS.

I suspect the fact that diabetes sufferers are 50/50 men and women whereas hypothyroidism affects mostly women has a lot to do with it.

[Judithdalston]

I note your comment Diogenes...in totally different academic branch (history) I knew of a number of researchers in same field who deliberately ‘hijacked’ or ignored work to get credit for new thinking! It’s a pig. Just hope that T3 and T4 combo if suits patients gets better trialled and adopted.

[Greekchick in reply to Judithdalston]

Hi Judith,

We have same problem in my field of academia as well. Let’s hope things change in thyroid despite the road getting there.

[diogenes Remembering in reply to Judithdalston]

One of my colleagues (won't say who) made the following comment on Bianco's deliberate omission of any of our work:

For me, this isn’t astonishing. Both Antonio Bianco and Elizabeth McAninch are repeatedly hostile to us. I don’t know why, because we didn’t do them any evil, and our research even confirms their findings (and vice versa). It must have to do with their personalities, not ours.

[loueldhen]

...and of course there's his patent of long-acting T3 ('LT3' - which they use but forget to define - tut tut).

[diogenes Remembering in reply to loueldhen]

The ref in the article is:

Da Conceicao RR, Fernandes GW, Fonseca TL, Bocco B, Bianco AC. Metal coordinated poly-zinc-liothyronine provides stable circulating triiodothyronine levels in hypothyroid rats. Thyroid. (2018) 28:1425–33. doi: 10.1089/thy.2018.0205

[loueldhen]

This hypothyroid rat (n=1) doesn't get palpitations or anxiety or any issues from only taking short acting T3. I hope LT3 will be useful to some and I hope they don't take away my T3 if LT3 doesn't work for me and yet again we are all forced to fit a particular hypothyroidism model.