Anyone switched from Slow Release T3 to direct / pure T3?

[GB44]

I would like to switch from SR T3 to direct T3 to try and control my dose better. My body is very sensitive to hormone changes so I want to do it as gently as possible. I still have hypo symptoms so plan to increase my dose in a couple more weeks but would rather switch to direct T3 if possible first. I am currently on 25mcg SR T3 per day which I take first thing in the morning (approx 5:30am). Any advice on how to break up direct T3 dose and how many times per day to try to make the switch as smooth as possible? Any other insights are appreciated- thanks!!

[shaws Administrator]

Re dosing with T3, I have followed advice from one of TUK's Advisers (deceased) and he was an expert in the use of T3. He himself took 150mcg of T3 daily, (in middle of night) as he had Thyroid Hormone Resistance which means he need larger doses which would knock others 'off their feet'.

The majority of us take normal doses. A normal dose is that which relieves all clinical symptoms.

He did not recommend splitting T3 doses as he stated that the T3 cells are not saturated and that when they are, they 'send out' " waves" throughout the day.

I take 25mcg T3 daily with one full glass of water and take it when I awake and wait an hour before eating. I am well. Obviously we're not all identical and there can be variations in doses.

The following link may be helpful:-

naturalthyroidsolutions.com...

[GB44 in reply to shaws]

Many many thanks! I so appreciate your insights. I will check out the link.

[Barrett582]

I began my T3 journey by working up to taking 7.5 mcg two times a day. I did this over about four months and stayed on the dose for about a year. With each dose I had about 30 minutes of feeling over medicated. I could feel definite highs and lows. I switched to compounded slow release T3, 15 mcg taken at 6:30 am. I really like this medication until something changed at the pharmacy and the medication did not work as well. Apparently there is an art to compounding T3. I then switched back to T3 tablets. I now take three 5 mcg for 15 mcg a day. I take 5 mcg at 6:30 am, 5 mcg at 10:00am, 5 mcg at 1:00 pm. I don’t worry about an empty stomach. With this regime I don’t feel highs an lows. I take 50 mcg T4 on an empty stomach at bedtime. I am quite sensitive to medications and medication changes. This works well for me, but everyone is different. Good luck.

[GB44 in reply to Barrett582]

Brilliant- thank you so much for your assistance. I really appreciate it!