Parathorone!?: A breakthrough at last, I may... - Thyroid UK

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Parathorone!?

LouiseM46 profile image
25 Replies

A breakthrough at last, I may eventually sees endocrinologist! But what is parathorone? Can anyone advise the significance..

many thanks

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LouiseM46 profile image
LouiseM46
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25 Replies
bantam12 profile image
bantam12

It's Parathormone and to do with the parathyroid glands, if calcium is normal and parathyroid only mildly raised they probably won't do anything.

LouiseM46 profile image
LouiseM46 in reply to bantam12

Thank you! Hoping it at the very lease gives me a chat with endocrinologist

Hi Louise the hormone is a another name for parathyroid hormone. I found an interesting article on how the hormone is secreted and it's affect on the level of calcium in your blood.

It also shows how it helps to convert vitamin D for your bones, and skin. Vitamin D deficiency may slow down the release of the parathyroid hormone. britannica.com/science is concise and easy to understand. Thank you for posting this as I have been told I am producing too much calcium which is affecting my dental health and probably my immune system

SlowDragon profile image
SlowDragonAdministrator

Have you had vitamin D, B12, folate and ferritin tested yet?

Vitamin D, calcium and parathyroid are all interlinked

LouiseM46 profile image
LouiseM46 in reply to SlowDragon

I can’t find vit D on printouts, I have asked for it a few times, will request it again on Friday at my next appointment.

Ferritin 6 (10-65)

B12 332 (180-900)

Folate 4.3 (2.1-14)

TSH 2.58 (0.27-4.20)

FREE T3 19 (12-22)

FREE T4 6.39 (3.1-6.8)

thyroglobulin. Antibodies 13.2 (0-115)

Peroxidase. Antibodies 18.7 (0-34)

SlowDragon profile image
SlowDragonAdministrator in reply to LouiseM46

Your ferritin is BELOW RANGE

Has GP done full iron panel? If not, they should have, to test for Anaemia

Ask GP for vitamin D test and perhaps coeliac blood test as possible cause of low vitamin levels

B12 and folate are both low

Probably not low enough for GP to treat

Supplementing a good quality daily vitamin B complex, one with folate in not folic acid may be beneficial.

B vitamins best taken in the morning after breakfast

Recommended brands on here are Igennus Super B complex. (Often only need one tablet per day, not two). Or Jarrow B-right

If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 3-5 days before any blood tests, as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

LouiseM46 profile image
LouiseM46 in reply to SlowDragon

Thank you, I will do. I was given ferrous fumarate 210g x3 daily for 28 days. Although I’m still very tired and pale. I have a full blood count done not sure about iron panel

These are the ones out with range;

Lymphocytes 3.1 (1-3)

Basophils 0 (0.02-0.1)

Mean Cell Volume 82.1 (83-101)

Mean cell harmoglobin 26.7 (27-32)

SlowDragon profile image
SlowDragonAdministrator in reply to LouiseM46

I don't know much about iron

Hopefully SeasideSusie or humanbean will comment

SeasideSusie profile image
SeasideSusieRemembering in reply to LouiseM46

Mean Cell Volume 82.1 (83-101)

Mean cell harmoglobin 26.7 (27-32)

Suggests iron deficiency anaemia, for which the correct treatment is 3 x ferrous fumarate daily.

Have you finished your 28 days? If so has GP retested? It can take many months to bring levels up. With a ferritin of 6 I would have thought an iron infusion was appropriate, that would bring level up within 24-48 hours.

An iron panel includes, besides ferritin, serum iron, TIBC and transferrin saturation.

LouiseM46 profile image
LouiseM46 in reply to SeasideSusie

Thank you I’m seeing GP on fri so will go over these points. I have finished the course but not been rechecked. Funnily enough they said my iron was only slightly under they at first advised no treatment then I represented with increasing symptoms and they prescribed tablets. Doesn’t give me much confidence.

Thank you for your input.

SeasideSusie profile image
SeasideSusieRemembering in reply to LouiseM46

If ever you are told again that your result for any test is "only slightly under" (or even slightly over), ask what ranges are for if they're going to be ignored. Your ferritin level is absolutely dire and your GP was negligent in saying that no treatment was needed. I'd like to see him/her function with such a miserable level.

LouiseM46 profile image
LouiseM46 in reply to SeasideSusie

Thanks perhaps the thyroid symptoms I keep presenting with are more a result of anemia, I didn’t realise it was so bad! I’ll keep pushing them

SeasideSusie profile image
SeasideSusieRemembering in reply to LouiseM46

Article on low ferritin which is interesting and helpful:

restartmed.com/low-ferritin/

These aren't particularly good either:

B12 332 (180-900)

Do you have any signs of B12 deficiency, you can check here b12deficiency.info/signs-an...

Plenty of people with serum B12 in the 300s have ended up on B12 injections.

I have read (but not researched so don't have links) that BCSH, UKNEQAS and NICE guidelines recommend:

"In the presence of discordance between test results and strong clinical features of deficiency, treatment should not be delayed to avoid neurological impairment."

You don't say what the unit of measurement for your B12 test is but an extract from the book, "Could it be B12?" by Sally M. Pacholok:

"We believe that the 'normal' serum B12 threshold needs to be raised from 200 pg/ml (or ng/L) to at least 450 pg/ml (or ng/L) because deficiencies begin to appear in the cerebrospinal fluid below 550".

"For brain and nervous system health and prevention of disease in older adults, serum B12 levels should be maintained near or above 1000 pg/ml (or ng/L)."

Folate 4.3 (2.1-14)

Folate is recommended to be at least half way through range. You can make sure you eat lots of folate rich foods, and supplement with a good B Complex containing 400mcg methylfolate (not folic acid) but don't start that if further investigation into your B12 is going to take place, folate/folic acid masks signs of B12 deficiency and should only be started after B12 injections or supplementation has been started.

LouiseM46 profile image
LouiseM46 in reply to SeasideSusie

Thanks! Great information, I do have many b12 deficiency symptoms. Also have been on stomach acid blocking medication for 14years so that won’t help absorption. Adjusting diet to help too

SlowDragon profile image
SlowDragonAdministrator in reply to LouiseM46

By stomach blocking medication, do you mean a PPI like omeprazole or Lansoprazole?

You will see hundreds of posts on here about low stomach acid caused by hypothyroidism. Far too frequently misdiagnosed as high acid

Almost identical symptoms, but very different treatment

If on a PPI you must NOT every stop this suddenly. It has to be weened off incredibly slowly. Other actions or supplements taken in its place, such as digestive enzymes, like Betane HCL, or slippery elm or apple cider vinegar

Read up as much as possible to learn about how intertwined gut function, low vitamins and poor thyroid are linked

PPI's cause low B12 and low magnesium

thyroidpharmacist.com/artic...

drmyhill.co.uk/wiki/hypochl...

scdlifestyle.com/2012/03/3-...

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu...

pulsetoday.co.uk/clinical/m...

gov.uk/drug-safety-update/p...

Gluten intolerance is often a hidden problem too. Going strictly gluten free can sometimes help with low stomach acid or reflux

Getting vitamins optimal is essential

Many on here find magnesium supplements extremely useful

Testing magnesium levels in blood is not really worth doing. The test rarely comes back abnormal, but many still find it helps

Also very common if magnesium is low vitamin D will be, or vice versa. Improving both together is recommended by many functional doctors

Government recommends everyone supplement October to April

gov.uk/government/news/phe-...

betterbones.com/bone-nutrit...

articles.mercola.com/sites/...

healthy-holistic-living.com...

articles.mercola.com/sites/...

betterbones.com/bone-nutrit...

Do NOT supplement any vitamin K if you take any blood thinning medication including aspirin

drsinatra.com/vitamin-k2-su...

Vitamin C and bones

healthimpactnews.com/2018/d...

The importance of sunshine

outsideonline.com/2380751/s...

easy-immune-health.com/magn...

But don't be surprised that GP or endo never mention gut, gluten or low vitamins. Hypothyroidism and poor gut function is very poorly understood by conventional medics.

A functional nutritionist or functional medic will treat the whole person. Looking at the interconnections between gut, food intolerances, vitamin deficiencies and advise on how to rebalance

Persistent low vitamins with supplements suggests coeliac disease or gluten intolerance

gluten.org/resources/health...

Vitamin D postal kit from NHS £29

vitamindtest.org.uk

LouiseM46 profile image
LouiseM46 in reply to SlowDragon

Thank you for all your advice. My Vit D is 38 I have been advised to take 800 supplement daily, gp suggested that could be the cause of higher parathormone. Have had iron checked again today as I’m sure that is still a problem. Still no further forward with thyroid and neck swelling unfortunately

SlowDragon profile image
SlowDragonAdministrator in reply to LouiseM46

NHS guidelines recommend 1600iu daily with vitamin D that low

clinox.info/clinical-suppor...

GP should probably be arranging iron infusion, as levels are so low. Or prescribing iron supplements, but this can take months to improve levels

Ask for coeliac blood test as possible cause of such poor vitamin levels

LouiseM46 profile image
LouiseM46 in reply to SlowDragon

I’ll try the higher dosage thanks! I mentioned coeliac but he didn’t respond, do you know where this could be done privately?

SlowDragon profile image
SlowDragonAdministrator in reply to LouiseM46

Plenty of coeliac tests available online for under £20

Easy to do, similar to the postal vitamin D test kit

LouiseM46 profile image
LouiseM46 in reply to SeasideSusie

Ferritin has increased to 21 from 6. Not currently on iron tablets, taking vit D and B12 supplements and have overhauled diet with iron rich foods.

Eyes very dry and corners of lips cracking, with heart palpitations. Should I be taking iron supplements at this level? I’m back within range 10-65 so I’m guessing doc not interested

SeasideSusie profile image
SeasideSusieRemembering in reply to LouiseM46

I've not seen that range before, it's usually 13-150 or 30-300 ish. Recommended is half way through the range. So with your range you're looking at 37.5. But I'm rather suspicious of your range as it's said that ferritin needs to be 70 for thyroid hormone to work. Is the unit of measurement for your range ug/L?

LouiseM46 profile image
LouiseM46 in reply to SeasideSusie

I noticed the male range is 36-225 ug/L quite a difference. Female under 45yrs 10-65 ug/L.

SeasideSusie profile image
SeasideSusieRemembering in reply to LouiseM46

The male range is usually higher, but I have never seen the female range that low. I've had ferritin tested with Medichecks, Blue Horizon and my GP. All use ug/L, GP range is 15-300 and the private ones 13-150.

LouiseM46 profile image
LouiseM46

I can’t find vit D on printouts, I have asked for it a few times, will request it again on Friday at my next appointment.

Ferritin 6 (10-65)

B12 332 (180-900)

Folate 4.3 (2.1-14)

TSH 2.58 (0.27-4.20)

FREE T3 19 (12-22)

FREE T4 6.39 (3.1-6.8)

thyroglobulin. Antibodies 13.2 (0-115)

Peroxidase. Antibodies 18.7 (0-34)

SlowDragon profile image
SlowDragonAdministrator

Read SeasideSusie or humanbean replies to many posts about low ferritin

GP should run full iron panel. Most likely need iron supplements, but may need iron infusion