Hi

[Kerri5778]

Current dose 100mcg levo diagnosed 2010 but didn't start treatment til 2014. Am I likely undermedicated?

TSH 10.6 (0.2 - 4.2)

Free T4 12.9 (12 - 22)

Thanks in advance

[bantam12]

You need to post your latest results so people can help you.

[Kerri5778 in reply to bantam12]

TSH 10.6 (0.2 - 4.2)

Free T4 12.9 (12 - 22)

[SlowDragon Administrator]

Yes very. Dose should be high enough to bring TSH down to around one and FT4 towards top of range

Make urgent appointment with your GP (or another in practice if yours has seen these and done nothing)

You need 25mcg dose increase and retesting in 6 weeks

Always take Levo on empty stomach and then nothing apart from water for at least an hour after. Many take on waking, but it may be more convenient and possibly more effective taken at bedtime

verywell.com/should-i-take-...

Many people find Levothyroxine brands are not interchangeable. Once you find a brand that suits you, best to make sure to only get that one at each prescription.

All thyroid tests should be done as early as possible in morning and fasting and if taking Levo don't take it in the 24 hours prior to test, delay and take straight after. This gives highest TSH and most consistent results

Ask GP to test vitamin D, Folate ferritin and B12. These are likely too low as result of being under medicated and may need supplementing

Also if not had thyroid antibodies tested ask that they are

Always get actual results and ranges on all tests

If you can not get full thyroid and vitamin testing from GP

thyroiduk.org.uk/tuk/testin...

Medichecks Thyroid plus ultra vitamin or Blue Horizon Thyroid plus eleven are the most popular choice. DIY finger prick test or option to pay extra for private blood draw. Both companies often have money off offers.

Dr Toft, past president of the British Thyroid Association and leading endocrinologist, states in Pulse Magazine,

"The appropriate dose of levothyroxine is that which restores euthyroidism and serum TSH to the lower part of the reference range - 0.2-0.5mU/l.

In this case, free thyroxine is likely to be in the upper part of its reference range or even slightly elevated – 18-22pmol/l. Most patients will feel well in that circumstance.

But some need a higher dose of levothyroxine to suppress serum TSH and then the serum-free T4 concentration will be elevated at around 24-28pmol/l.

This 'exogenous subclinical hyperthyroidism' is not dangerous as long as serum T3 is unequivocally normal – that is, serum total around T3 1.7nmol/l (reference range 1.0-2.2nmol/l)."

You can obtain a copy of the article by emailing [e-mail] print it and highlight question 6 to show your doctor.

[Kerri5778 in reply to SlowDragon]

Thyroid peroxidase antibodies 348 (<34)

Thyroglobulin antibodies >1300 (<115)