I' ve pondered deeply about why the thyroid medical establishment is so against and ignores the new evidence that shows that TSH-only diagnosis in therapy and forbidding of T3 in any form for treatment of hypothyroidism are badly mistaken ideas. You would think that medical opinion would carefully assess new work in the light of their current opinions and change as necessary. I've come to the conclusion that in a strange sense, it's all the fault of the late Drs Lowe and Skinner. By that I mean that they were advocating much of what the new ideas promote, not from a particularly physiologically-based detailed argument but from a presentational point of view by the patients. At that time, the physiological detail wasn't there to strengthen their case, in the face of the popular opposing paradigm that TSH is all. Therefore they could not only be ignored, but hounded as being "quacks" who damage their patients. In this way there is developed a stubborn mindset against the idea that Lowe & Skinner might have been right all along in most ways, since if this is acknowledged, there will be a lot of egg on many faces. The medical profession is far too sensitive of their reputation to let that happen if they can avoid it. For my part I haven't come to the conclusions I now have because of Lowe & Skinner but have independently found it to be true it purely from a neutral biochemical/physiological viewpoint. I find that very interesting because our group didn't set out to go in that direction initially: but the signpost came in to view early on, and could not be denied.