I found this 'history' fascinating and awful as well. Thank Goodnes in this day and age we have thyroid hormone replacements.
Then, in 1877, William Miller Ord, read his paper before the Royal Medical and Chirurgical Society of London and proposed the term ‘myxoedema’ for the adult condition (Ord 1878). He described the non-pitting, ‘mucous oedema’. He also described how the hands of one of his patients went ‘dead’ when she attempted to sew. This was possibly due to carpal tunnel syndrome, a potential complication of hypothyroidism, but then an unknown entity. Ord ended his paper carefully, stating that: ‘… the name [myxoedema] is only intended to represent the condition, and does not profess to involve an explanation of its causes.’ However, he described the ‘practical annihilation’ of the thyroid gland he found at autopsy, and went on to discuss the possible relevance of this, attempting a synthesis of the earlier reports by Curling (1850) and Fagge (1871).