I was diagnosed with hypo last year and am currently on 50 mcg levo. Recently I've noticed that after more than a glass or two of wine (and Irrespective of whether or not I feel the effects at the time) I wake up about 3am with a rapid, pounding heartbeat. This lasts an hour or two and is really frightening. The next morning I'm fine (though sleep deprived). Is this a reaction to the levo do you think? Or another symptom of hypothyroidism?