Hyperthyroidism and cortisol : Hi all, I am... - Thyroid UK

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Hyperthyroidism and cortisol

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Hi all,

I am hyperthyroid and for my next blood test my endo would like to include a test for cortisol. Does anyone know the link with hyper and why it would be done? I have had lots of blood tests before but not familiar with testing for cortisol.

Thanks.

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Clutter profile image
Clutter

Em_776,

Information re thyroid and cortisol in this link google.co.uk/search?q=Hyper...

in reply to Clutter

Many thanks for the reply.

I had a quick Google search before posting but found most articles on hyper were in medical journals. Was after a slightly more simplified response or any users experience of how their cortisol levels have affected their hyperthyroidism.

Slightly confused why they would be testing for it. Are they looking for it as a cause of hyper or is it another side effect from the condition? My understanding of my Grave's is that it is due to the high levels of antibodies.

Very confused, sorry!

sulamaye profile image
sulamaye in reply to

Cortisol and thyroid work together. Often if uv been hypo for sometime cortisol can be low, or struggling where it often gets high working so hard to deal with the stress to the body of being hypo before crashing. Cortisol is not just a stress hormone it is, like thyroid, essential for life. There is also a relationship between cortisol and how thyroid is taken up, I can't remember what order, but basically low or high cortisol can effect the cells taking up the t3 they need. Stress, which can be physical or emotional stress, often leads to low cortisol, although that can be high in the blood, but low in a saliva stress test, because it is not bioavailabile t the body. This is the case for me because I have m,e/ CFS .

Clutter profile image
Clutter in reply to

Em-776,

There were links on Cortisol from TiredThyroid, Hypothyroidmom and StopTheThyroidMadness (STTM) in the Google link I posted which will explain Cortisol in an accessible way.

High levels of TSI or TRab antibodies confirm Graves Disease which is autoimmune hyperthyroid disease.

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Hanne1977 profile image
Hanne1977

Hi there...Sorry this may be long. But I have Cushing’s disease, a pituitary Adema. I had brain surgery twice in 2015 to remove the tumor and the gland on my right side. There were several awful side effects I had for year and a half. I became diabetic, hypothyroid, producing too much ATCH. The pituitary is the master gland, and controls the thyroid the adrenal gland‘s and sex organs. So essentially most of the glands mentioned are affected by anything involved in the pituitary. This condition is more commonly called hyper cortisolism. High cortisol levels can cause hypothyroidism and hyper thyroidism. I found out in March that I have another tumor and what’s left of my gland. I chose to take an experimental medication instead of having surgery or radiation. The medication is called Korlym and costs 20,000 a month! Fortunately, they were free through national organization of rare diseases the medication is free. In My case, my last blood test for my TSH was 7.140! The normal range I think is between 2.000 or ye my case, my last blood test for my TSH was 7.140! The normal range I think is between 2.000 And 4.00. Meaning I now have hyper thyroidism. Basically, it means you are producing too much of a Specific hormone (something that starts with thx). The Hyperthyroidism causes too much of they T3 and T4.

My endocrinologist says this is due to the Korlym. This medication is a progesterone blocker. Progesterone turns to cortisol in the body, Which then turns to Cortisol. The Korlym Prevents excess cortisol reaching the pituitary gland.

I do have some valuable advice for you. If your endocrinologist is testing your cortisol levels and it’s just a 24 hour urine collection, when I had full-blown Cushing’s disease, it would not show up in the 24 hour urine. There are blood tests to see if your levels are high. My results were always normal for the blood test. It did show the Cortisol being high from A dexamethasone test and a cortisol saliva test. I also had something called IPSS done which was not easy but it showed definitively that there was a tumor.I do have some valuable advice for you. If your endocrinologist is testing your cortisol levels and it’s just a 24 hour urine And blood tests show the Cortisol is normal, keep pressing the endocrinologist to do theDexamethasone tests and the Salivary cortisol test. It took me 15 years and five different endocrinologists to find out I had the Cushing’s disease or hyperCortisolism. So Your endocrinologist is probably Checking your pituitary cortisol levels to see if that is causing overproduction of your Thyroid.

I am a researcher And a graduate psychology and clinical counseling. Student. I have learned through my studies, About peer reviewed journals concerning any type of medical condition. Fortunately, I have access to every journal in the world for free. Anybody can write an article on Wikipedia or Google that does not have cited sources. For a journal article to be published as peer-reviewed is a very complex process. the research can take years and at least three or four years of revisions before it gets approved by a panel of doctors. You will find more information and journals, which you had mentioned you have Found. And if you’re not used to scientific or medical jargon it’s like reading another language. If you would like I can email you some of the articles that will not have a lot of the jargon. I research that may help you and can email you. Please keep in mind how complex the entire endocrine system is, it took me time to absorb all the information. My struggle has be 18 years in the making! Sometimes I get depressed and when I go there, I try to find a positive. Right now that is presenting information to individuals to help them to not feel alone and misunderstood. Learning aboutHypercortisolism and The thyroid disorders adrenal insufficiency and reproductive disorders has led me to the point I now know that I will be writing my dissertation on endocrine disorders and how they affect clinical mental health Illnesses.

I love what I have said is my based on my experience and the knowledge I have learned. I am not an endocrinologist, so I don’t know everything I hope other read a verse don’t believe that I’m saying Pure medical fact

I wish you much luck and hope you find solutions. Just remember keep fighting.

helvella profile image
helvellaAdministratorThyroid UK in reply to Hanne1977

When you see a user name of Hidden, it means that the person is no longer a member of this forum.

We often close posts that were originated by people who have left - there is no point in wasting our time making replies. Occasionally, the thread might still be active and popular and will be left. More often, it is simply a case of none of the admins noticing!

I shall not be closing this post to replies - at least for now. However, I do very much recommend that you post your question/story as a new post so that you get the best possible number of people seeing and responding.

Hanne1977 profile image
Hanne1977 in reply to helvella

Thank you so much! I did post my response as a new discussion.

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