Pregnenolone

[JellyJac]

Hi there I have a quick question. I got pregnenolone today. My question is I take my thyroid tablets at 7am I take all my supplements at 12pm away from my thyroid med so they absorb, and take more thyroid med at 4pm, do I take the pregnenolone with my thyroid med as they are a hormone, or separately from everything?

[shaws Administrator]

I don't have an answer as I don't take pregnenelone but why not take all your thyroid meds at one time and you have space in the p.m. for pregnenelone.

[JellyJac in reply to shaws]

Thanks Shaws, I am on a very large dose of NDT/T3 and thought it may be best to spread it out? Although it would be more convenient to take it all in am.

[shaws Administrator in reply to JellyJac]

I didn't know your prescription. I have read this link and this is an excerpt. I think you could take it along with your second dose but be gradual as it can increase the effect of thyroid hormones so you might have to reduce your dose:-

Pregnenolone

Pregnenolone or “the mother of all hormones” is made from cholesterol mainly in the adrenal glands. As its name suggests, it is the precursor to all of your sex hormones including testosterone, estrogen, progesterone, DHEA and cortisol. Pregnenolone is found in its highest concentration in the brain and is important for memory and brain function. Research has shown that those with low thyroid function also have low pregnenolone levels. We use time-released pregnenolone in our patients with adrenal fatigue to rebuild the adrenal glands when they are exhausted. Most of the pregnenolone taken will convert into cortisol which is good if the adrenal glands are exhausted and not producing enough cortisol. Remember that too much cortisol inhibits thyroid function but on the flip side you need some cortisol to convert inactive T4 into active T3. Patients tend to notice an instant increase in energy and memory and have an improved sense of well-being once they begin taking pregnenolone.

drhedberg.com/hormone-thyro...

Ray Peat, Ph.D., has written about the effect of other hormones on the thyroid system. Progesterone and pregnenolone tend to increase thyroid hormone effects because they promote the conversion of T4 to the more active T3.

drkaslow.com/html/thyroid.html

[JellyJac]

Ah that is great information Shaws, Thanks, I have looked at loads of info on pregnenolone, bu none is as clear as this.

It seems as though it mat assist with conversion so hopefully I may not need as much thyroid meds. I will take this pm with my NDT/T3. fingers crossed.