Weight gain due to overmedication?: Have read a... - Thyroid UK

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Weight gain due to overmedication?

morebeans profile image
22 Replies

Have read a couple of things which have said that weight gain could potentially be caused by OVERmedication with thyroid meds. Is this true and, if so, can anyone explain how it works?

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morebeans
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22 Replies
HIFL profile image
HIFL

Too much T3 causes insulin resistance. This is the beginning of Type 2 diabetes. tiredthyroid.com/blog/2012/...

morebeans profile image
morebeans in reply toHIFL

Thanks for the link :).

Interesting as I DO have blood sugar issues. Don't think I'm the sharpest tool in the box at the moment as I can't quite get my head round whether my being hypoglycemic means I'm insulin resistant (since LOW blood sugar is my problem and it never goes abnormally high). Also I've had some degree of reactive hypoglycemia through all levels of medication. Guess I need to do more research on insulin and blood sugar to try to properly understand what's going on.

Have been on T3 only for a wee while as it seemed like I had rT3 issues, but I need to get back to the T4/T3 mix that I'm officially on before my next endo appointment. It may be that I've overdone the T3, tho', apart from some hot flushes, I don't feel overmedicated.

I really do need to lose some weight round my middle, but needing to eat at least every 2 hours so as not to get the shakes makes it difficult. Why is nothing ever simple?!

HIFL profile image
HIFL in reply tomorebeans

If you're getting physical shakes, that means your cortisol is probably too low, and all that T3 is just clearing out your cortisol faster!

Sineadkots profile image
Sineadkots in reply toHIFL

Oh wow this is happening to me ! I think I was taking too much as i' e gained weight! What should I do ??

Thank you

shaws profile image
shawsAdministrator

I would say that weight gain, which is a clinical symptom of hypothyroidism and might be the initial symptom patients have. Usually when on optimum medication the weight would reduce again as our metabolism would be raised by levo (if it converts to sufficient T3).

Some also have weight gain which might be due to the doctor only giving you sufficient levo to bring your TSH 'within range' when in fact most of us a need a TSH of around 1 or lower to feel well overall.

morebeans profile image
morebeans

Thanks, Shaws. Haven't had a test for 6 months, but my TSH is generally almost non-existant and I still can't get into any of my trousers!

I lost some weight after I first started treatment, but my middle has just gradually thickened again. I'm fortunate in that I've always been naturally fairly slim (until my hypo took hold) but if I ate normally now, I would just keep gaining weight.

greygoose profile image
greygoose in reply tomorebeans

Weight round the middle sounds like cortisol problems.

morebeans profile image
morebeans in reply togreygoose

Have to admit that I know very little about cortisol issues. My endo checked my adrenal function (short synacthen test) after he diagnosed my Hashi's and said it was ok, so I didn't look any further into it.

Yet another thing to research!

greygoose profile image
greygoose in reply tomorebeans

But the short synacthen test will only tell you if you have Addisons or Cushings. It doesn't take account of anything in between. That's why they always say it's OK! They actually have no idea about adrenal fatigue which is in between. :(

What you need is a 24 hour cortisol test to see what's really going on, but you won't get that on the NHS!

morebeans profile image
morebeans in reply togreygoose

Thanks Grey, will have a look at symptoms of adrenal fatigue and see if more than my expanding middle fits the picture.

greygoose profile image
greygoose in reply tomorebeans

:)

QUE6T-33 profile image
QUE6T-33 in reply togreygoose

Hi Greygoose - just read your comment Weight Gain round

Middle sounds like cortisol problems. Would that Cortisol

high or low - or either ? Thanks,

greygoose profile image
greygoose in reply toQUE6T-33

Either, I think. But Don't quote me on that! :)

QUE6T-33 profile image
QUE6T-33 in reply togreygoose

Yep, guess either way, it prevents uptake Thyroid

hormone.  

helvella profile image
helvellaAdministrator

We see quite a few hyperthyroid people who admit to having very good appetites when hyper. Obviously this is a general observation and might or might not apply in any individual case. It seems reasonable to suggest that over-medication with thyroid hormone could have the same effect.

morebeans profile image
morebeans in reply tohelvella

I have a hyperthyroid friend who is incensed because she is really overweight!

Don't think my appetite has increased - I've had to adjust to eating more often because of blood sugar issues, but try to compensate for this by having smaller meals.

I do need to really try and get my head round the whole blood sugar metabolism thing - not just in case it's relevant to my weight gain, but also to learn how to keep my levels steadier.

Clutter profile image
Clutter

Morebeans, this link may help explain thyroid.about.com/od/thyroi...

Why don't you order a private thyroid test to check levels in case you've overshot

thyroiduk.org.uk/tuk/testin...

morebeans profile image
morebeans

Thanks, Clutter. Think that first link is where I first saw there was a possibility of a connection between weight gain and overmedication. It doesn't seem to give an explanation of what the mechanism for this is, though. There are links onto other interesting bits of info though, so I'll go for a wonder through them!

Have never had a private test done before. I live out in the middle of nowhere, so getting a blood sample taken might be tricky - will check this out in case I get desperate.

Clutter profile image
Clutter in reply tomorebeans

Morebeans, BH & Genova in the link I posted do postal home testing finger prick blood tests. Widely used on the forum.

morebeans profile image
morebeans in reply toClutter

That certainly makes it more feasible, thanks Clutter.

frenny28 profile image
frenny28 in reply tomorebeans

The medication shuts down your thyroid hormones, which subsequently turn off your metabolism! So frustrating!

frenny28 profile image
frenny28

Yes... My doctor overmedicated me with methimazole and I literally gained 30lbs in a weekend, had severe depression, and the beta blocker she gave me lowered my heart rate to almost nothing (could not feel my pulse or hear me breathing for 12+ hours). This nearly cost me my job. Then... They diagnosed me with a "Weight Disorder" from the weight gain caused by their overmedication!!! I am so pissed and annoyed!

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