Aphasia and Hypothyroidism

[LeslieBrian]

To add to my previous claim for cholesterol and T3.

"The Osborne lab has already obtained data suggesting that thyroid hormone regulation and cholesterol

metabolism are linked through SREBP-2. The data suggested that in the presence of high T3 levels

(hyperthyroidism), the TR/RXR heterodimer activatesSREBP-2 which in turn results in LDL receptor activation. In the presence of a greater number of LDLR units, more cholesterol is taken up by cells and

therefore serum cholesterol levels decline. However, as mentione d above, this mechanism is only half the

story."

From: urop.uci.edu/grants/sample_...

[PR4NOW]

Interesting grant request from the Univ of Calif Irvine. The file date is 2-12-2014 so I wonder if they completed the study and published results. And why did you stop taking T3 if it was working? PR

[LeslieBrian in reply to PR4NOW]

And why did you stop taking T3 if it was working? PR.

Being a male I had a prostate problem fixing it was a great release. Became invincible once again and as a thyroid test (including T3!) suggested all was just OK I just cut T3. Should have monitored the outcome!

I'll post on how I'm approaching T3 once bloods are available.

Les

[Angel_of_the_North]

I did read a study somewhere that suggested that too much T3 and insufficient T4 caused aphasia. My cholesterol hasn't really changed in 30 years (only on meds for two).