Thyroid UK
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Sertraline and levothyroxine

I've just discovered that sertraline is most likely causing issues with my levothyroxine.

I upped sert to 100 from 75 a few days after going from 150 to 175 thyroxine. (Diff drs)

The dr who is managing thyroid is good and referred to endo but it's 6 weeks away. I'm three weeks into the upped doses. Briefly felt less pain on Saturday, now feeling the muscular skeletal stuff I've been struggling with again.

Just wondering about what to do. The sert really helps by brain focus but I suspect making things worse long term. Never had the physical pain I've had this year before.

2 Replies

Sorry have reported as a question


I'm experiencing a similar problem currently after spending 4 years on 50mg Sertraline for controlling menopausal night sweats while taking 225mcg Levothyroxine for hypothyroidism. I now feel as I did 16 years ago when first diagnosed with an under active thyroid.


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