Giving up is never the answer, however easy it seems at times. Having watched my mother with ME since I was 14 I do know what sufferers go through. She's had two different diagnosed strains of ME and her health is not brilliant anyway. I have just been diagnosed with Fibro although I suspect the thyroid is to blame.
The trick is to keep strong in your mind. Never give in despite the pain. My mum was wheelchair bound years ago and told she'd never get out of it. She got out of it because it terrified her, the idea of being in it the rest of her life. She can now walk miles at a time.
A lot of it is mindset. You could try finding a local Reiki practitioner and even hypnotherapy. Some places do special rates for such things (we have a place in St Austell that charges whatever you can afford for half hour sessions once a week, she is an ME suffferer too). Look for local support groups to find others like yourself that you can talk to, even if it's on the phone or messaging online. It's always good to know you're not alone, which you are not!
If the medications are troublesome you need to speak to your doctor or specialist. If they aren't helpful then find another doctor. Not easy, I know when you're already ill and little things are hard but it helps to give you a focus and give you something to keep trying for.
Just remember, we are all here and on other sites and so many are feeling what you feel. As a group we become stronger with the support it provides. Keep smiling.