Pilot case-control study: Gastric herpes simplex virus type 1 infection is associated with functional gastrointestinal disorders (FGIDs) in the presence and absence of comorbid fibromyalgia: a pilot case–control study
Gastric herpes simplex virus type 1 (HSV-1) infection, as indicated by ICP8 presence, was significantly associated with FGIDs in the presence (OR 70.00, 95% CI 7.42–660.50; P < .001) and absence (OR 38.50, 95% CI 3.75–395.40; P < .001) of comorbid FM. Neither histological gastritis nor H. pylori infection were found to be associated with FGIDs or FM.
Conclusions
HSV-1 infection was identified in gastric mucosal biopsies from patients with diverse FGIDs, with and without comorbid FM. Larger, multi-center studies investigating the prevalence of this association are warranted.
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Meleber
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Hi I have had IBS d for at least 35years. The worry and stress get me down. Doctors are no help. I am on Mirtazapine anti depressants, which do not help . I just about cope with all the symptoms but feel I will become a hermit soon. I have suffered with cold sores all my life (apparently even had them as a baby) so I know I have Herpes Simplex. Could that be why I suffer?
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