Amitryptaline and IBS… waiting for it to work! - IBS Network

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Amitryptaline and IBS… waiting for it to work!

Dolly32 profile image
11 Replies

I’ve been taking amitryptaline (10mg) for about 4 weeks, to try and tame my long time IBS-D. So far, it’s not working too well. Causing constipation, excessive gas, bloating and then every few days I will have to go to the toilet urgently all day…

Has anyone had a similar experience, and if so, is it worth sticking with it to see improved results?

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Dolly32 profile image
Dolly32
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11 Replies
Luisa22 profile image
Luisa22

You should definitely tell your doctor, or who prescribed it. Maybe a lower dose is needed? I don't know. I have never taken it. It's best to speak to them first before trying a lower dose, because I don't know enough about it.

Sunnyday21 profile image
Sunnyday21

Amitryptaline has been a wonder drug for me. I think it would probably be worthwhile persevering for a few more weeks. I’ve been taking 10mg for around 10 months and I have had no episodes of IBS-D since. I’d had a few years of really debilitating episodes and suffered complete fatigue. The only initial side effect was feeling a bit groggy in the morning, but that has since passed. May not be for everyone but it’s certainly worth a try. Hope you find something that works for you.

Dolly32 profile image
Dolly32 in reply toSunnyday21

I really am hoping this will be the thing that gets it’s under control. It definitely has improved how often I have a proper attack of it, but I still can’t say a real reduction in symptoms. I’ll give it another week or so at this dose, and see where we get to.

Glitterpants profile image
Glitterpants in reply toDolly32

I have been taking Amitriptylene for 4 years and it has certainly calmed my stomach down. When I first took it , the tabs did make me constipated and a dry mouth but side effects wore off after a few months.

Dolly32 profile image
Dolly32 in reply toGlitterpants

Dosage? I’m deffo going to stick at it for a longer period, sounds like it’s worth trying!

Antiques72 profile image
Antiques72 in reply toSunnyday21

I am on 3-4 a night … best thing I have tried …I stay away from fibre and try to eat small meals every day brother than load my stomach … buscopan is great ..take two 20 minutes before food …

Dolly32 profile image
Dolly32 in reply toAntiques72

Oh I’ve never tried them before a meal, only after / if I get the pain. Will try that too!

AMerchant profile image
AMerchant

I have been taking Amitriptyline 10mg for 2 months now. I have acid reflux issues

Although it hasn't really helped me with the stomach pain but it has certainly helped with my sleep.

I had some constipation initially but that went away by drinking at least 1 litre water daily

Dolly32 profile image
Dolly32 in reply toAMerchant

Yes, I am off to buy a bigger water bottle today to help! (It’s definitely reduced my acids reflux I haven’t taken a PPI for a week!)

Mush83 profile image
Mush83

Maybe give your GP a call. I was on 10mg and after a few weeks it didn’t appear to be helping much. She upped it to 20mg and it really does help.

Dolly32 profile image
Dolly32

It’s definitely having an effect but not to the level I was dreaming of 😂 my doc told me to feel feee to increase up to 30mg, I’m reluctant as I’m so tired as it is in the mornings, but I think I will give 20 a go

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