I'm new to this site can anyone help me? I was diagnosed with IBS in my teens (I'm now 48) but have been chronically constipated all my life, apparently on medication as a baby. I completed drug research in 1992 at Hospital & was given manevac which worked for 12 years. When it stopped working I had to have a spinchterotomy and then I was given manevac. This worked well for another 12 or so years but now I have been struggling for the last 18 months again. Doctor has given me bisocodyl but they gripe me and bloat me-does anyone know any other medication which might help me?