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Xtandi
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Help with next steps please
Failed
xtandi
, zytiga, docetaxel. I know hospice is around the corner and we are also waiting phone calls on a couple of immunotherapy trials. My question is there anything left to try at this point?
Failed
xtandi
, zytiga, docetaxel. I know hospice is around the corner and we are also waiting phone calls on a couple of immunotherapy trials. My question is there anything left to try at this point?
Dalipup
in
Advanced Prostate Cancer
5 years ago
Fatigue, Pain & Other Fun Stuff
Since then he’s had casodex, lupron, 6 of taxotere, Zytiga, 9 of cabazitazel + carboplatin,
Xtandi
, Keytruda, 6 more of cabazitazel + carboplatin, 5 days of radiation for pain in his hip, and has had the first of Radium 223.
Since then he’s had casodex, lupron, 6 of taxotere, Zytiga, 9 of cabazitazel + carboplatin,
Xtandi
, Keytruda, 6 more of cabazitazel + carboplatin, 5 days of radiation for pain in his hip, and has had the first of Radium 223.
Luv2fish
in
Advanced Prostate Cancer
5 years ago
Anyone taking Darolutamide develope asthenia, a known side effect? I've read similar SEs with Xtandi, so is this with all lutamide drugs?
My husband, who is mCRPC started Darolutamide 1 month ago. Shortly after, he started to become more weak in his legs, esp his knees. Last week, after taking Darolutamide for 3-1/2 weeks he suddenly developed asthenia (abnormal physical weakness or lack of energy). I had to run out and buy him a walker
My husband, who is mCRPC started Darolutamide 1 month ago. Shortly after, he started to become more weak in his legs, esp his knees. Last week, after taking Darolutamide for 3-1/2 weeks he suddenly developed asthenia (abnormal physical weakness or lack of energy). I had to run out and buy him a walker
JLS1
in
Advanced Prostate Cancer
5 years ago
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STREAM. Enzalutamide + ADT with Salvage Radiation in high-risk PSA-recurrent PCa after RP
However, the addition of 6 months of
XTANDI
may change the nature of surviving PCa cells. Half of the men progressed within 3 years. How did prior
XTANDI
use affect their overall survival?
However, the addition of 6 months of
XTANDI
may change the nature of surviving PCa cells. Half of the men progressed within 3 years. How did prior
XTANDI
use affect their overall survival?
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Albumin protein in urine
He takes
Xtandi
. Also has a permanent urine catheter, doctors don't want to operate. He has Parkinson and heart arrhythmia. Has anyone had this before?
He takes
Xtandi
. Also has a permanent urine catheter, doctors don't want to operate. He has Parkinson and heart arrhythmia. Has anyone had this before?
JuanVV
in
Advanced Prostate Cancer
5 years ago
Xtandi v Zytiga v Docetaxel
I have been told I am now Stage 4- PSA doubled in past 2 months from 6-14, T now is 51 after 3rd Lupron shot, with sabbatical to every 6 mos. Onc gave me these 3 options along with Patient Education from Kaiser. After reading about possible side effects, has anyone had experience and suggestions for
I have been told I am now Stage 4- PSA doubled in past 2 months from 6-14, T now is 51 after 3rd Lupron shot, with sabbatical to every 6 mos. Onc gave me these 3 options along with Patient Education from Kaiser. After reading about possible side effects, has anyone had experience and suggestions for
arete1105
in
Advanced Prostate Cancer
5 years ago
Dr says Enzalutimide... what about Cabazitaxel?
Doctor recommends
Xtandi
(enzalutimide). I'm wondering about going back to chemo first with Cabazitaxel.
Doctor recommends
Xtandi
(enzalutimide). I'm wondering about going back to chemo first with Cabazitaxel.
Tak-Druk
in
Advanced Prostate Cancer
5 years ago
What to do next for treatment
My onc put me on
Xtandi
which worked for 7-8 mos but now PSA after going back down to 6.5 it slowly rose to over 22. The two main options he is talking about include a PARP inhibitor the first one is a UCLA trial in conjunction with immunotherapy (Katruda). The other is just the PARP inhibitor.
My onc put me on
Xtandi
which worked for 7-8 mos but now PSA after going back down to 6.5 it slowly rose to over 22. The two main options he is talking about include a PARP inhibitor the first one is a UCLA trial in conjunction with immunotherapy (Katruda). The other is just the PARP inhibitor.
sjpoli46
in
Advanced Prostate Cancer
5 years ago
PSA measures and Chemo
I am continuing with
Xtandi
and Lupron during the chemo.
I am continuing with
Xtandi
and Lupron during the chemo.
Shepard
in
Advanced Prostate Cancer
5 years ago
Paper published about my vaccine treatment
I did have Keytruda added in July, 2018, and did
Xtandi
for almost two years before stopping it a month ago. My SUV barely budged no matter what was added after the initial regression of around 30 tumors so it was collectively agreed that removing my prostate was the best course of action.
I did have Keytruda added in July, 2018, and did
Xtandi
for almost two years before stopping it a month ago. My SUV barely budged no matter what was added after the initial regression of around 30 tumors so it was collectively agreed that removing my prostate was the best course of action.
Fuzzman77
in
Advanced Prostate Cancer
5 years ago
PSA Up During Docetaxel, Scan indicates progression. Determined, Next step??
Or Jetvana vs
XTandi
? Thought it wouldn't be so fast.... he's been so fit, now he still drags himself on his usual route up and down hill, hurts to bend down. MO also will check on pain issue. I admit I'm shook up..... and motivated .... Glad you're here. .....
Or Jetvana vs
XTandi
? Thought it wouldn't be so fast.... he's been so fit, now he still drags himself on his usual route up and down hill, hurts to bend down. MO also will check on pain issue. I admit I'm shook up..... and motivated .... Glad you're here. .....
Barbara345
in
Advanced Prostate Cancer
5 years ago
Why is xtandi so expensive?
Why is
xtandi
so expensive.?
Why is
xtandi
so expensive.?
Bobcat64
in
Advanced Prostate Cancer
5 years ago
Chemo One More Time
Since September 2017, I have had 16 infusions (2 rounds of 6 cycles and most recent round of 4 cycles) of this same treatment, with rechallenges of
Xtandi
in between. Last round and the round beginning tomorrow includes
Xtandi
PLUS chemo combo.
Since September 2017, I have had 16 infusions (2 rounds of 6 cycles and most recent round of 4 cycles) of this same treatment, with rechallenges of
Xtandi
in between. Last round and the round beginning tomorrow includes
Xtandi
PLUS chemo combo.
vandy69
in
Advanced Prostate Cancer
5 years ago
Still confused on next step
MO wants to put me on
Xtandi
. I have had some suggestions including radiation and using MO Kwon’s oligmetestatic protocol and proton therapy. Still on Xgeva which was started with ADT. Any comments or suggestion would be very much appreciated. Thanks
MO wants to put me on
Xtandi
. I have had some suggestions including radiation and using MO Kwon’s oligmetestatic protocol and proton therapy. Still on Xgeva which was started with ADT. Any comments or suggestion would be very much appreciated. Thanks
Bobcat64
in
Advanced Prostate Cancer
5 years ago
Clinical Trial
My PSA is trndinup after 2.5 years on
Xtandi
. One of my doctors s talking to me about a clinical trial called LAE001/ Prednisone with Afuresertib.
My PSA is trndinup after 2.5 years on
Xtandi
. One of my doctors s talking to me about a clinical trial called LAE001/ Prednisone with Afuresertib.
Jrb12
in
Advanced Prostate Cancer
5 years ago
What now? Help for Taxman, please!
I Have been on
Xtandi
,Zytiga, Radium shots and have been on Lupron for years. My PSA this month just rose from 45 to 68. I have not had chemo because I have a low white blood cell count ( though this blood test showed it to be the highest its ever been so it now may be an option.
I Have been on
Xtandi
,Zytiga, Radium shots and have been on Lupron for years. My PSA this month just rose from 45 to 68. I have not had chemo because I have a low white blood cell count ( though this blood test showed it to be the highest its ever been so it now may be an option.
taxman
in
Advanced Prostate Cancer
4 years ago
Confused xtandi or zytiga
MO on xgeva Psa steadily increasing to 12.3 now wants me on
xtandi
. Scared about what to do? Age 79 active and in great shape.
MO on xgeva Psa steadily increasing to 12.3 now wants me on
xtandi
. Scared about what to do? Age 79 active and in great shape.
Bobcat64
in
Advanced Prostate Cancer
5 years ago
PSA vs PSMA
Last October I started
Xtandi
, which I still take. It along with the Lupron has my PSA at 0.2 or 0.3. I am wondering if I get another PSMA PET scan now will it show anything with my PSA so low? Is there a direct relationship between PSA level and PSMA expression?
Last October I started
Xtandi
, which I still take. It along with the Lupron has my PSA at 0.2 or 0.3. I am wondering if I get another PSMA PET scan now will it show anything with my PSA so low? Is there a direct relationship between PSA level and PSMA expression?
xpbdb
in
Advanced Prostate Cancer
5 years ago
Currently looking at adding one of these...
Same is true for
Xtandi
, correct? Thank you.
Same is true for
Xtandi
, correct? Thank you.
Parscore
in
Advanced Prostate Cancer
5 years ago
Darolutamide vs Proxalutamide - for a Hail Mary??
He has High AR Amplification, ARL702H 93.5% (which our MO says means
Xtandi
likely won't work), ART878A 0.6% and some "Variants of uncertain significance": ARM750T 2.2%, ARM750V 1.5%. ATME1612Q 0.2%.
He has High AR Amplification, ARL702H 93.5% (which our MO says means
Xtandi
likely won't work), ART878A 0.6% and some "Variants of uncertain significance": ARM750T 2.2%, ARM750V 1.5%. ATME1612Q 0.2%.
JLS1
in
Advanced Prostate Cancer
5 years ago
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