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Xtandi
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After Zofigo, what next?
My husband just finished 6 sessions of Zofigo (Ra223), which his doctor (MO) recommended after he failed Lupron in 12/21, and then
Xtandi
in 11/22. He weathered it great, with only mild digestive issues and he continues to be asymptomatic.
My husband just finished 6 sessions of Zofigo (Ra223), which his doctor (MO) recommended after he failed Lupron in 12/21, and then
Xtandi
in 11/22. He weathered it great, with only mild digestive issues and he continues to be asymptomatic.
Tinuriel
in
Advanced Prostate Cancer
10 months ago
5/25 update on Zytiga failed
Is
Xtandi
the next step ? Am I overreacting and should wait a couple of months for the next blood test. I would appreciate any thoughts from all of you.
Is
Xtandi
the next step ? Am I overreacting and should wait a couple of months for the next blood test. I would appreciate any thoughts from all of you.
alperk
in
Advanced Prostate Cancer
1 year ago
Oncologist and prostate surgeon conflicting treatment
In September last year Oncologist prescribed
xtandi
and lucrin for 2 years and radiation to the pelvic area.
In September last year Oncologist prescribed
xtandi
and lucrin for 2 years and radiation to the pelvic area.
Jbooopin
in
Advanced Prostate Cancer
10 months ago
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Erratic PSA and broken bone
I'm resuming chemo this Friday due to PSA spike and staying on
Xtandi
. Any thoughts as to why my PSA was so erratic lately with the sudden drop to 0.023 and then spike to 6.9? Could it be stress related to the broken bone? Thanks.
I'm resuming chemo this Friday due to PSA spike and staying on
Xtandi
. Any thoughts as to why my PSA was so erratic lately with the sudden drop to 0.023 and then spike to 6.9? Could it be stress related to the broken bone? Thanks.
MechD
in
Advanced Prostate Cancer
1 year ago
xtandi users
We have
xtandi
that husband can't use, he had terrible reaction to it. Any users in us that need this, I will ship to you rather than waste it.
We have
xtandi
that husband can't use, he had terrible reaction to it. Any users in us that need this, I will ship to you rather than waste it.
Spring15-3
in
Advanced Prostate Cancer
1 year ago
Xofigo Update
When it started to fail a year ago they added
Xtandi
. Now that is no longer working and have completed 5 of 6 treatments of Xofigo - which he is tolerating well (blood counts are holding up, with only minor indigestion/diarrhea.
When it started to fail a year ago they added
Xtandi
. Now that is no longer working and have completed 5 of 6 treatments of Xofigo - which he is tolerating well (blood counts are holding up, with only minor indigestion/diarrhea.
Tinuriel
in
Advanced Prostate Cancer
1 year ago
We could tell in advance if enzalutamide works on a patient: computational biology
hopefully it will be clinically tested soon ”For the study in Nature Communications, Mitrofanova's team developed computational algorithms to discover why the prostate cancer drug enzalutamide (sold under the brand name
Xtandi
) never works for some patients and why it eventually stops working in others
hopefully it will be clinically tested soon ”For the study in Nature Communications, Mitrofanova's team developed computational algorithms to discover why the prostate cancer drug enzalutamide (sold under the brand name
Xtandi
) never works for some patients and why it eventually stops working in others
Maxone73
in
Advanced Prostate Cancer
3 months ago
Lymph node treatments
Note my PSA has risen from 0.27 in November to .49 in April I started
Xtandi
in June 2022 when my PSA was 0.69 and it quickly dropped to 0.40 in July but has slowly but steadly climbed back up Is the rise in PSA a result of this mild progression of disease in the lymph nodes or resistance to
Xtandi
Note my PSA has risen from 0.27 in November to .49 in April I started
Xtandi
in June 2022 when my PSA was 0.69 and it quickly dropped to 0.40 in July but has slowly but steadly climbed back up Is the rise in PSA a result of this mild progression of disease in the lymph nodes or resistance to
Xtandi
Ian996
in
Advanced Prostate Cancer
1 year ago
What after docetaxel?
My NHS oncologist told me today that the
Xtandi
I am currently being prescribed might last for the remainder of this year and possibly next.
My NHS oncologist told me today that the
Xtandi
I am currently being prescribed might last for the remainder of this year and possibly next.
BrentW
in
Advanced Prostate Cancer
11 months ago
Pluvicto works but at what cost
Previously on Firmagon,
Xtandi
worked for awhile, nothing with Xofigo and a few rounds of Jevtana didn’t help and caused problems, also had localized XRT - but had to have chemo to qualify for Pluvicto which is a great advanced treatment for many of us After multiple delays getting Pluvicto with PSA
Previously on Firmagon,
Xtandi
worked for awhile, nothing with Xofigo and a few rounds of Jevtana didn’t help and caused problems, also had localized XRT - but had to have chemo to qualify for Pluvicto which is a great advanced treatment for many of us After multiple delays getting Pluvicto with PSA
Beach18
in
Advanced Prostate Cancer
10 months ago
EMBARK trial results reported
Pfizer reported results of the EMBARK trial testing
Xtandi
+Lupron or
Xtandi
alone against Lupron+Placebo.
Seems that hormone-sensitive patients may be able to choose
alone and avoid Lupron. This applies to patients who had no metastases on CT/bone scan.
Pfizer reported results of the EMBARK trial testing
Xtandi
+Lupron or
Xtandi
alone against Lupron+Placebo.
Seems that hormone-sensitive patients may be able to choose
alone and avoid Lupron. This applies to patients who had no metastases on CT/bone scan.
GP24
in
Advanced Prostate Cancer
1 year ago
Our Pluvicto story
My husband didn't have success with
Xtandi
or Zytiga. MO feels that cabitaxel is our next best step. Genetic testing has been done with no actionable findings. I know that many are not able to complete all 6 Pluvicto treatments and many aren't able to have any success at all.
My husband didn't have success with
Xtandi
or Zytiga. MO feels that cabitaxel is our next best step. Genetic testing has been done with no actionable findings. I know that many are not able to complete all 6 Pluvicto treatments and many aren't able to have any success at all.
Yadifan
in
Advanced Prostate Cancer
10 months ago
Prednisone tapping
Dr suggested to start taking
Xtandi
,but to this day I have not taken it because my PCP found out a dangerous interaction with retroviral meds I take for HIV. Now after reading what SE
XTandi
could do to you, I am so glad I haven't started taking it yet!
Dr suggested to start taking
Xtandi
,but to this day I have not taken it because my PCP found out a dangerous interaction with retroviral meds I take for HIV. Now after reading what SE
XTandi
could do to you, I am so glad I haven't started taking it yet!
Blueribbon63
in
Advanced Prostate Cancer
1 year ago
Good news
But for the second time a 3 month period on only 80mg
Xtandi
has failed to have any adverse affect on my progression - I now consider that 80mg is keeping the beast at bay just as well as 120mg was - but the fatigue is much lighter. Makes me happy --- hope it continues for many years.
But for the second time a 3 month period on only 80mg
Xtandi
has failed to have any adverse affect on my progression - I now consider that 80mg is keeping the beast at bay just as well as 120mg was - but the fatigue is much lighter. Makes me happy --- hope it continues for many years.
Stoneartist
in
Advanced Prostate Cancer
1 year ago
Xtandi monotherapy is very effective
(Zoom your browser to read the image) At the AUA2023 the results of the EMBARK trial were presented. This phase 3 randomized trial had three arms and compared in patients with high-risk biochemically recurrent prostate cancer: - enzalutamide plus leuprolide - enzalutamide monotherapy - placebo plus
(Zoom your browser to read the image) At the AUA2023 the results of the EMBARK trial were presented. This phase 3 randomized trial had three arms and compared in patients with high-risk biochemically recurrent prostate cancer: - enzalutamide plus leuprolide - enzalutamide monotherapy - placebo plus
GP24
in
Advanced Prostate Cancer
1 year ago
Update on failing Enzalutamide
Brief recent history: a couple of years ago PSA started to rise on the treatment that had worked well (bicalutamide and 3 monthly Prostap injections) So I switched to
Xtandi
just over a year ago. The side effects were horrendous, so I reduced dosage to one-quarter of usual dose.
Brief recent history: a couple of years ago PSA started to rise on the treatment that had worked well (bicalutamide and 3 monthly Prostap injections) So I switched to
Xtandi
just over a year ago. The side effects were horrendous, so I reduced dosage to one-quarter of usual dose.
CrocodileShoes
in
Advanced Prostate Cancer
10 months ago
Xtandi failure?
My Onco said that I needed to stop
Xtandi
whatever the PSA resuls, but I'm obviously scared about what happens when I have nothing but the injection. If PSA doubles while on
Xtandi
every 2 months, what will it do when I am not taking anything?
My Onco said that I needed to stop
Xtandi
whatever the PSA resuls, but I'm obviously scared about what happens when I have nothing but the injection. If PSA doubles while on
Xtandi
every 2 months, what will it do when I am not taking anything?
CrocodileShoes
in
Advanced Prostate Cancer
1 year ago
Xtandi/Kaiser/Socal/Medicare
Im debating moving to
Xtandi
from Zityga. I would appreciate knowing from anyone here on
Xtandi
while on Medicare with Kaiser? What is the Part D copay you are paying?? (Before the donut hole.) Thanks in advance.
Im debating moving to
Xtandi
from Zityga. I would appreciate knowing from anyone here on
Xtandi
while on Medicare with Kaiser? What is the Part D copay you are paying?? (Before the donut hole.) Thanks in advance.
Hidden
in
Advanced Prostate Cancer
1 year ago
Pluvicto Update
I'm also taking
Xtandi
and of course the beloved Lupron. I think it has been better tolerated than Docetaxel but the fatigue may be worse. Not sure if Pluvicto is to blame or the
Xtandi
. I am very weak and tire easily. I did walk a mile the other day but I was wiped out afterwords.
I'm also taking
Xtandi
and of course the beloved Lupron. I think it has been better tolerated than Docetaxel but the fatigue may be worse. Not sure if Pluvicto is to blame or the
Xtandi
. I am very weak and tire easily. I did walk a mile the other day but I was wiped out afterwords.
bglendi53
in
Advanced Prostate Cancer
1 year ago
Xtandi (enzalutamide) alone is superior to ADT alone at preventing metastases in "high-risk" recurrent men
Xtandi
monotherapy performed significantly better than ADT alone. No comparison yet on
Xtandi
monotherapy vs
Xtandi
+ADT. Also improved time to PSA progression/castration-resistance and time to chemo. No data yet on overall survival.
Xtandi
monotherapy performed significantly better than ADT alone. No comparison yet on
Xtandi
monotherapy vs
Xtandi
+ADT. Also improved time to PSA progression/castration-resistance and time to chemo. No data yet on overall survival.
Tall_Allen
in
Advanced Prostate Cancer
1 year ago
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