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Relugolix (Orgovyx) superior to Lupron and no T flare.
https://clinicaltrials.gov/ct2/show/results/NCT03085095?term=testosterone
https://clinicaltrials.gov/ct2/show/results/NCT03085095?term=testosterone
Hidden
in
Advanced Prostate Cancer
3 years ago
Relugolix
Has anyone tried
Relugolix
in place of Lupron for ADT ??? Pros/Cons??? Thank you!!!
Has anyone tried
Relugolix
in place of Lupron for ADT ??? Pros/Cons??? Thank you!!!
JolleySprings
in
Advanced Prostate Cancer
3 years ago
Apalutamide & Relugolix
His preference is a combo of apalutamide and
relugolix
but his MO seems reluctant because he "hasn't seen any data." Anyone out there on this combo? How long? Results? Unusual side effects? Thanks to all.
His preference is a combo of apalutamide and
relugolix
but his MO seems reluctant because he "hasn't seen any data." Anyone out there on this combo? How long? Results? Unusual side effects? Thanks to all.
sturn
in
Advanced Prostate Cancer
3 years ago
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ADT hot flash treatment: Paxil vs. Pycnogenol?
Am taking
Relugolix
to lower PSA and am experiencing hourly nighttime hot flashes that deny me a restful night's sleep. My MO recommends Paxil or Pycnogenol to alleviate the hot flashes.
Am taking
Relugolix
to lower PSA and am experiencing hourly nighttime hot flashes that deny me a restful night's sleep. My MO recommends Paxil or Pycnogenol to alleviate the hot flashes.
novatimo
in
Advanced Prostate Cancer
3 years ago
Does anyone have a testimony about how Oral Relugolix they are on is going?
Is anyone using Oral
Relugolix
? It looks like I will likely have to go back on Androgen-Deprivation Therapy, and I'm wondering if anyone has any personal information they have with it? How much after insurance are you paying? If you've had Luprin before, is this better?
Is anyone using Oral
Relugolix
? It looks like I will likely have to go back on Androgen-Deprivation Therapy, and I'm wondering if anyone has any personal information they have with it? How much after insurance are you paying? If you've had Luprin before, is this better?
MobilityTech
in
Advanced Prostate Cancer
3 years ago
Relugolix / Orgovyx
Anyone having issue with obtaining
Relugolix
? Not the script/prescription by your oncologist, but after that... How did you get it? Local pharmacy? Or is it something else, direct drop ship from manufacturer of drug? I'm having difficulty...
Anyone having issue with obtaining
Relugolix
? Not the script/prescription by your oncologist, but after that... How did you get it? Local pharmacy? Or is it something else, direct drop ship from manufacturer of drug? I'm having difficulty...
Cooolone
in
Advanced Prostate Cancer
3 years ago
New pill instead of 3 month shots
has anybody taking
relugolix
yet and if so how much did you pay per month?
has anybody taking
relugolix
yet and if so how much did you pay per month?
Muffin2019
in
Advanced Prostate Cancer
3 years ago
Has anyone taken Relugolix pills? How did they affect you?
Has anyone taken
relugolix
pills in place of Lupron shots? After over two years on Lupron my oncologist is putting me on
Relugolix
. Any advice on this?(
Has anyone taken
relugolix
pills in place of Lupron shots? After over two years on Lupron my oncologist is putting me on
Relugolix
. Any advice on this?(
Jamtu27
in
Advanced Prostate Cancer
3 years ago
My Personal "trial" of Cyclic Testosterone Therapy
And then he would consider
relugolix
(oral ADT) for the fast-on and fast-off properties.
And then he would consider
relugolix
(oral ADT) for the fast-on and fast-off properties.
MateoBeach
in
Advanced Prostate Cancer
3 years ago
Effects on the gut and heart of Orgovyx (Relugolix) vs Lupron
How does the Orgovyx (
Relugolix
) affect the gut microbiome since you are swallowing it as opposed to an injection of Lupron? 2. The NP told me that Orgovyx (
Relugolix
) is less stressful on your heart than Lupron. Any idea if thats true?
How does the Orgovyx (
Relugolix
) affect the gut microbiome since you are swallowing it as opposed to an injection of Lupron? 2. The NP told me that Orgovyx (
Relugolix
) is less stressful on your heart than Lupron. Any idea if thats true?
GeorgeGlass
in
Advanced Prostate Cancer
4 years ago
Any comments / knowledge of new ADT treatment?
https://investors.myovant.com/news-releases/news-release-details/myovant-sciences-announces-fda-approval-orgovyxtm-
relugolix
https://investors.myovant.com/news-releases/news-release-details/myovant-sciences-announces-fda-approval-orgovyxtm-
relugolix
Lyubov
in
Advanced Prostate Cancer
4 years ago
FDA has approved Relugolix (Orgovyx) for advanced PCa.
The most common AE across all grades in both arms was hot flash, occurring in 54.3% and 51.6% of the
relugolix
and leuprolide cohorts, respectively. There was a higher incidence of all-grade diarrhea with
relugolix
at 12.2% versus 6.8% with leuprolide.
The most common AE across all grades in both arms was hot flash, occurring in 54.3% and 51.6% of the
relugolix
and leuprolide cohorts, respectively. There was a higher incidence of all-grade diarrhea with
relugolix
at 12.2% versus 6.8% with leuprolide.
pjoshea13
in
Advanced Prostate Cancer
4 years ago
Relugolix
Has anyone heard if & when
Relugolix
will be approved by FDA. I am hoping in December as was once thought
Has anyone heard if & when
Relugolix
will be approved by FDA. I am hoping in December as was once thought
Nigu-1
in
Advanced Prostate Cancer
4 years ago
Orgovyx (relugolix) ADT pills will be available in January 2021
Myovant is predicting Orgovyx (
relugolix
) will be available next month, according to their website. An internet site says Orgovyx carries a list price of $2,313 per bottle containing 30 pills (ouch!).
Myovant is predicting Orgovyx (
relugolix
) will be available next month, according to their website. An internet site says Orgovyx carries a list price of $2,313 per bottle containing 30 pills (ouch!).
Tall_Allen
in
Advanced Prostate Cancer
4 years ago
Orgovyx (relugolix) is "now available through authorized specialty distributors."
https://investors.myovant.com/news-releases/news-release-details/myovant-sciences-announces-us-availability-orgovyxtm-treatment I don't know who the distributors are or which drug plans already cover it.
https://investors.myovant.com/news-releases/news-release-details/myovant-sciences-announces-us-availability-orgovyxtm-treatment I don't know who the distributors are or which drug plans already cover it.
Tall_Allen
in
Advanced Prostate Cancer
4 years ago
FDA) today approved relugolix (Orgovyx) for the treatment of adult patients with advanced prostate cancer.
https://www.medscape.com/viewarticle/942933?nlid=138790_3901&src=wnl_newsalrt_201218_MSCPEDIT&uac=399617CV&impID=2746365&faf=1
https://www.medscape.com/viewarticle/942933?nlid=138790_3901&src=wnl_newsalrt_201218_MSCPEDIT&uac=399617CV&impID=2746365&faf=1
mrssnappy
in
Advanced Prostate Cancer
4 years ago
Please guide on Medical oncologist's advice
Would also like to know about
relugolix
. Sorry for too many questions
Would also like to know about
relugolix
. Sorry for too many questions
Nirman
in
Advanced Prostate Cancer
4 years ago
NO MORE SHOTS (SOON) Urologist won't be happy!! bye bye lupron
https://www.onclive.com/view/fda-grants-priority-review-to-
relugolix
-for-advanced-prostate-cancer?eKey=ZGd3aXpAbGV3aXMtYXF1YXRlY2guY29t
https://www.onclive.com/view/fda-grants-priority-review-to-
relugolix
-for-advanced-prostate-cancer?eKey=ZGd3aXpAbGV3aXMtYXF1YXRlY2guY29t
Longterm101
in
Advanced Prostate Cancer
4 years ago
Relugolix versus Leuprolide - Neal Shore video.
The difference of 7.9 percentage points (95% CI, 4.1 to 11.8) showed noninferiority and superiority of
relugolix
(P<0.001 for superiority). All other key secondary end points showed superiority of
relugolix
over leuprolide (P<0.001).
The difference of 7.9 percentage points (95% CI, 4.1 to 11.8) showed noninferiority and superiority of
relugolix
(P<0.001 for superiority). All other key secondary end points showed superiority of
relugolix
over leuprolide (P<0.001).
pjoshea13
in
Advanced Prostate Cancer
4 years ago
Relugolix for Androgen-Deprivation Therapy in Advanced Prostate Cancer The New England Journal of Medicine
Sustained castrate-level testosterone suppression (primary endpoint) was superior with
relugolix
(97% vs 89% through 48 weeks). In addition, cardiovascular event risk was lower with
relugolix
.
Sustained castrate-level testosterone suppression (primary endpoint) was superior with
relugolix
(97% vs 89% through 48 weeks). In addition, cardiovascular event risk was lower with
relugolix
.
Balsam01
in
Advanced Prostate Cancer
4 years ago
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