Has anyone taken Relugolix pills? How did they affect you?

[Jamtu27]

Has anyone taken relugolix pills in place of Lupron shots? After over two years on Lupron my oncologist is putting me on Relugolix. Any advice on this?(

[JPnSD]

So far so good. The hot flashes were my main side effect..with Firmagon...and they seem less frequent and intense with Orgovyx. Also don't miss the 3-4 days of debilitating pain and swelling from the Firmagon shots. Happy I made the switch.

[Jamtu27 in reply to JPnSD]

Thank you! It's encouraging to to see your positive experience!

[Longterm101 in reply to Jamtu27]

I’ve been on the meds for 60 days

No issues

[StayingOptimistic in reply to JPnSD]

My pain from the Firmagon lasts 10 days. I hate it.

[maley2711]

are they insurer-covered? Medicare?

[JRPnSD in reply to maley2711]

Start with your insurance if Advantage MEDICARE....see what they say. They are all over the place since it is new. Mine was $850...but got 2 months free from Myovant to start and a grant to pay the copay for 2021.

[Jamtu27 in reply to maley2711]

Yes, medicare and GIC insurance are covering the cost.

[wilcoxsaw]

Been on Orgovyx a month, few hot flashes about the same as with firmagon, PSA has dropped to a lower number than it was on firmagon, a month ago it was less than 0.014, yesterday less than 0.003, T is 8. Fatigue and loss of strength are minor I'm still able to work out at the gym 3 hours a day 4 days a week with weights and Cardio. I have gained no body weight.

My Blue Cross PPO supplement covers the drug at a $50 per month co-pay.

[Jamtu27 in reply to wilcoxsaw]

Thank you for the positive info!

[NewPotatoCaboose in reply to wilcoxsaw]

How are things going with it now at around 2 months?

[wilcoxsaw in reply to NewPotatoCaboose]

no change to what I wrote above, mild hot flashes, less endurance and stamina ( same as with firmagon) , that's it.

[reb77 in reply to wilcoxsaw]

I'm going to start Orgovyx in 2 weeks. How old are you to be so active? Thanks.

[wilcoxsaw in reply to reb77]

66

[reb77 in reply to wilcoxsaw]

Ok. Good for you!

[podsart]

Don’t seem to understand why there appears to be resistance to the vantas implant use . As u describe it , sounds advantageous

[podsart]

Makes sense

[Jamtu27]

I'm not aware of Vantas implants. Is it an ADT alternative?

[Jamtu27]

Thanks for the info!

[Cooolone]

The one advantage I can see, and it's entirely an opinion mind you, is that with pills, the amount of drug your body will have daily is more stabilized vs an injection of a specific amount of drug that is eventually wearing off. T levels were monitored during trials vs Lupron and there is better ramps with Relugolix, or quicker to castrate levels when starting the drug, and quicker reduction when stopped. This also bodes well for patients that may experience the worst of SE's as if they stop the therapy, they don't have to wait for the injection to wear off, sometimes months.

Otherwise, it does exactly the same thing.

I will be switching to it in a month or so as my Lupron shot wears off.

Best Regards

[Jamtu27 in reply to Cooolone]

Thank you! How long have you been on Lupron?