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European Commission OKs Lupkynis for Active Lupus Nephritis
European Commission OKs Lupkynis for Active Lupus
Nephritis
The oral therapy was approved in the US in 2021 by Marisa Wexler, MS | September 22, 2022 The European Commission has approved Lupkynis (voclosporin) to treat active lupus
nephritis
, a serious complication of systemic lupus erythematosus
European Commission OKs Lupkynis for Active Lupus
Nephritis
The oral therapy was approved in the US in 2021 by Marisa Wexler, MS | September 22, 2022 The European Commission has approved Lupkynis (voclosporin) to treat active lupus
nephritis
, a serious complication of systemic lupus erythematosus
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
2 years ago
Itolizumab Shows Promise For Lupus Nephritis Patients in Early Trial Data
nephritis
.”
nephritis
.”
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
2 years ago
Kyverna Asks FDA to Begin Clinical Test on Lupus Nephritis Treatment
The filing of this IND for KYV-101 in lupus
nephritis
is an important milestone for Kyverna and we are excited by the prospect of KYV-101 opening a new era in the care of patients with [lupus
nephritis
],” Peter Maag, PhD, Kyverna’s CEO, said in a press release.
The filing of this IND for KYV-101 in lupus
nephritis
is an important milestone for Kyverna and we are excited by the prospect of KYV-101 opening a new era in the care of patients with [lupus
nephritis
],” Peter Maag, PhD, Kyverna’s CEO, said in a press release.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
2 years ago
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Anxious about totally bizarre symptoms
I suffered
Nephritis
as a child (60 years ago) and have since then had no kidney problems except passing a kidney stone around 5 years ago. For the past 5 or 6 nights I have been woken with quite severe pain in the area of my right kidney.
I suffered
Nephritis
as a child (60 years ago) and have since then had no kidney problems except passing a kidney stone around 5 years ago. For the past 5 or 6 nights I have been woken with quite severe pain in the area of my right kidney.
Loobs39
in
Kidney Disease
2 years ago
Black SLE patients at 19 times higher risk of early heart disease
risk of cardiovascular disease (CVD) starts early after diagnosis and is strikingly high in Black people with lupus and those who present with renal disease and discoid rash (a chronic skin presentation of lupus),’’ Shivani Garg, MD, the study’s first author and the director of the Lupus and Lupus
Nephritis
risk of cardiovascular disease (CVD) starts early after diagnosis and is strikingly high in Black people with lupus and those who present with renal disease and discoid rash (a chronic skin presentation of lupus),’’ Shivani Garg, MD, the study’s first author and the director of the Lupus and Lupus
Nephritis
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
1 year ago
Phase 2 Trial Tests Daxdilimab as Potential DLE Therapy
“Daxdilimab is also being investigated in other autoimmune conditions that are driven by high levels of interferon, including alopecia areata, dermatomyositis, lupus
nephritis
and systemic lupus erythematosus,” Podrebarac said.
“Daxdilimab is also being investigated in other autoimmune conditions that are driven by high levels of interferon, including alopecia areata, dermatomyositis, lupus
nephritis
and systemic lupus erythematosus,” Podrebarac said.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
1 year ago
Interstitial/Tubulointerstitial nephritis
Hi everyone, Has anyone here been diagnosed with interstitial
nephritis
/tubulo-interstitial
nephritis
due to pyelonephritis? Thank you
Hi everyone, Has anyone here been diagnosed with interstitial
nephritis
/tubulo-interstitial
nephritis
due to pyelonephritis? Thank you
Gotroot
in
Kidney Disease
2 years ago
HCQ: do we need to pay more attention to serious ocular side effects!👆
But dermatology says it’s nephrology because of my lupus
nephritis
which had flared with a dosage increase around that time,😳🥺😟! GP scratching her head offering no answers. No ophthalmology appt as yet so to be safe I’ve stopped it myself .
But dermatology says it’s nephrology because of my lupus
nephritis
which had flared with a dosage increase around that time,😳🥺😟! GP scratching her head offering no answers. No ophthalmology appt as yet so to be safe I’ve stopped it myself .
Betty909090
in
LUPUS UK
2 years ago
working with lupus- help and advice please
hello lovely people , advice please I’m trying to do a part time job with lupus / lupus
nephritis
, bit b12 deficiency, tender kidneys, muscle and joint pains , fatigue and re occurring kidney infection. I’m on mycrophenolate and steroids ... my energy levels are poor after my shift.
hello lovely people , advice please I’m trying to do a part time job with lupus / lupus
nephritis
, bit b12 deficiency, tender kidneys, muscle and joint pains , fatigue and re occurring kidney infection. I’m on mycrophenolate and steroids ... my energy levels are poor after my shift.
Bellissimo
in
LUPUS UK
2 years ago
Alliance Backs SLE Research by Minority Scientists
This work will provide an opportunity to better understand lupus
nephritis
in a high-risk and understudied patient group.
This work will provide an opportunity to better understand lupus
nephritis
in a high-risk and understudied patient group.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
2 years ago
TIN, nocturia/polyuria, kidney pain
Hello all, I wonder if anyone here has been diagnosed with tubulointerstitial/interstitial
nephritis
and is dealing with nocturia polyuria and daytime polyuria. How do you deal with this disease, is there anything that can reduce the urine volume especially during the night?
Hello all, I wonder if anyone here has been diagnosed with tubulointerstitial/interstitial
nephritis
and is dealing with nocturia polyuria and daytime polyuria. How do you deal with this disease, is there anything that can reduce the urine volume especially during the night?
Gotroot
in
Kidney Disease
2 years ago
[i][b]DxTerity Test to Guide SLE Therapy Now Available in All 50 US States[/b][/i]
These patients tend to have more severe disease symptoms, and they are at an increased risk of developing lupus
nephritis
— a form of lupus-related kidney inflammation that can be severe.
These patients tend to have more severe disease symptoms, and they are at an increased risk of developing lupus
nephritis
— a form of lupus-related kidney inflammation that can be severe.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
2 years ago
LUPUS
This last month my oxygen saturation levels have been sitting around 92-95% and just this week following numerous blood tests have had a positive dsDNA test so they have added Lupus to my list and urgent referral back to Rheumatology as the high level is suggestive of Lupus
Nephritis
.
This last month my oxygen saturation levels have been sitting around 92-95% and just this week following numerous blood tests have had a positive dsDNA test so they have added Lupus to my list and urgent referral back to Rheumatology as the high level is suggestive of Lupus
Nephritis
.
1STEP
in
LUPUS UK
2 years ago
VOLUNTEER EXPERT PATIENTS NEEDED - Moderate/Severe Lupus Nephritis for NICE Appraisal of Voclosporin
Hi everyone, NICE recently announced that they will be conducting a Health Technology Appraisal (HTA) for the use of voclosporin with immunosuppressives for treating lupus
nephritis
- https://www.nice.org.uk/guidance/indevelopment/gid-ta10878 Voclosporin is a new drug for the treatment of lupus
nephritis
Hi everyone, NICE recently announced that they will be conducting a Health Technology Appraisal (HTA) for the use of voclosporin with immunosuppressives for treating lupus
nephritis
- https://www.nice.org.uk/guidance/indevelopment/gid-ta10878 Voclosporin is a new drug for the treatment of lupus
nephritis
Paul_Howard
LUPUS UK
in
LUPUS UK
2 years ago
Mechanism Discovered Behind Strongest Lupus Genetic Risk Factor
These mice showed higher levels of SLE-causing, anti-double-stranded DNA antibodies and kidney tissue changes that resembled those of lupus
nephritis
, a serious form of kidney inflammation in SLE patients.
These mice showed higher levels of SLE-causing, anti-double-stranded DNA antibodies and kidney tissue changes that resembled those of lupus
nephritis
, a serious form of kidney inflammation in SLE patients.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
2 years ago
Lupus Nephritis and Cyclophosphamide
I'm 23 and got diagnosed with SLE and lupus
nephritis
a year ago in March. I've never had the
nephritis
treated until recently however. I take 400mg hydroxychloroquine (I should take 300mg based on weight though) and have always been on 10mg of prednisolone.
I'm 23 and got diagnosed with SLE and lupus
nephritis
a year ago in March. I've never had the
nephritis
treated until recently however. I take 400mg hydroxychloroquine (I should take 300mg based on weight though) and have always been on 10mg of prednisolone.
CPower
in
LUPUS UK
2 years ago
Mechanism Discovered Behind Strongest Lupus Genetic Risk
These mice showed higher levels of SLE-causing, anti-double-stranded DNA antibodies and kidney tissue changes that resembled those of lupus
nephritis
, a serious form of kidney inflammation in SLE patients.These findings highlight that, in the presence of IFN-gamma, the protein coded by “the single most
These mice showed higher levels of SLE-causing, anti-double-stranded DNA antibodies and kidney tissue changes that resembled those of lupus
nephritis
, a serious form of kidney inflammation in SLE patients.These findings highlight that, in the presence of IFN-gamma, the protein coded by “the single most
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
2 years ago
Steroid dependent membranous nephritis
Hlo everyone. This is my first post and i so eagerly want ur views about my condition. I am 37 years old south Asian male.i was first diagnosed with proteinuria in 2007 and biopsy result showed Minimal change disease.i was given occasional steroids in various forms till 2011.remission occured and went
Hlo everyone. This is my first post and i so eagerly want ur views about my condition. I am 37 years old south Asian male.i was first diagnosed with proteinuria in 2007 and biopsy result showed Minimal change disease.i was given occasional steroids in various forms till 2011.remission occured and went
Sajjadsadique
in
Kidney Disease
2 years ago
Advice with Prednisolone Taper
So, I stayed at that dose for 10 months until January when my new rheumatologists took action for lupus
nephritis
. I was first increased to 20mg at the end of January, then 40mg at the beginning of February following a kidney biopsy.
So, I stayed at that dose for 10 months until January when my new rheumatologists took action for lupus
nephritis
. I was first increased to 20mg at the end of January, then 40mg at the beginning of February following a kidney biopsy.
CPower
in
LUPUS UK
2 years ago
New, targeted therapy inhibits specific immune cells associated with lupus nephritis
, and was effective in improving kidney inflammation in animal models of lupus and lupus
nephritis
.
, and was effective in improving kidney inflammation in animal models of lupus and lupus
nephritis
.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
2 years ago
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