Experiences with
Ibrutinib2,003 public posts
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Explainer: what is the blood-brain barrier and how can we overcome it?
As the article mentioned, small molecules can pass through the blood-brain barrier and Ibrutinib appears to have a promising role in treating CLL infiltration of the CNS: http://www.bloodjournal.org/content/127/19/2356?
Dr. Matt Davids on the combination of TGR-102 and ibrutinib
Matthew Davids from ASH 2016 where we discuss a clinical trial that combines two targeted therapies for treating relapsed/refractory CLL, ibrutinib and TGR-1202.