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Cabazitaxel
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First CT scan tomorrow after starting new treatment
I was accepted on a trial for
cabazitaxel
in January. It is licenced for advanced prostate cancer and is similar to paciltazol which is used for advanced breast cancer, but is given every 3 weeks instead of weekly and is supposed to have fewer / less severe side effects.
I was accepted on a trial for
cabazitaxel
in January. It is licenced for advanced prostate cancer and is similar to paciltazol which is used for advanced breast cancer, but is given every 3 weeks instead of weekly and is supposed to have fewer / less severe side effects.
Julie2233
in
SHARE Metastatic Breast Cancer
4 years ago
Cabazitaxel and lungs
Has anyone experienced lung problems while undergoing
Cabazitaxel
chemotherapy?
Has anyone experienced lung problems while undergoing
Cabazitaxel
chemotherapy?
annjohannsen
in
Advanced Prostate Cancer
4 years ago
PSMA in circulating tumor cells is a new poor prognostic marker for castration-resistant PCa - Plos One - Published: January 27, 2020
Several drugs available for sequential therapy of CRPC, such as enzalutamide (ENZ), abiraterone (ABI), docetaxel (DOC),
cabazitaxel
(CBZ) and radium-223, have been shown to prolong the survival of CRPC patients [2].
Several drugs available for sequential therapy of CRPC, such as enzalutamide (ENZ), abiraterone (ABI), docetaxel (DOC),
cabazitaxel
(CBZ) and radium-223, have been shown to prolong the survival of CRPC patients [2].
cujoe
in
Fight Prostate Cancer
4 years ago
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ASCO GU 2020: Additional Mechanism of Action of PARP Inhibitor Talazoparib Attacks Prostate Cancer Cells, Spares Normal Cells
All had received docetaxel and 49% had received prior
cabazitaxel
. The overall objective response rate was 25.6% (95% confidence interval, 13.5-41.2). The objective response rate in BRCA1/2-positive patients was 50.0% (95% confidence interval, 27.2-72.8).
All had received docetaxel and 49% had received prior
cabazitaxel
. The overall objective response rate was 25.6% (95% confidence interval, 13.5-41.2). The objective response rate in BRCA1/2-positive patients was 50.0% (95% confidence interval, 27.2-72.8).
Balsam01
in
Advanced Prostate Cancer
4 years ago
Next steps -questions on immunotherapy
In the meantime my husband went into his second line of chemo,
cabazitaxel
, to get us to February . Well as many of you who are on this waitlist knows they have stopped enrolling due to a change in protocols. Unfortunately the chemo is not doing it's kind and my husband's psa has shot up to 300.
In the meantime my husband went into his second line of chemo,
cabazitaxel
, to get us to February . Well as many of you who are on this waitlist knows they have stopped enrolling due to a change in protocols. Unfortunately the chemo is not doing it's kind and my husband's psa has shot up to 300.
Dalipup
in
Advanced Prostate Cancer
4 years ago
Darolutamide vs Proxalutamide - for a Hail Mary??
Diagnosed 3yrs ago and did the Casodex, then Docetaxel chemo, then RT to the L4-L1 followed by 1 round of
Cabazitaxel
+ Carboplatin (for mets in liver).
Diagnosed 3yrs ago and did the Casodex, then Docetaxel chemo, then RT to the L4-L1 followed by 1 round of
Cabazitaxel
+ Carboplatin (for mets in liver).
JLS1
in
Advanced Prostate Cancer
4 years ago
Small Cell Neuroendocrine PC Update
So he will begin 4 cycles of combo chemo
cabazitaxel
+carboplatinum (taxane for the pc fellas and platinum for the neuroendocrine fellas). It would be to toxic for him to combine the chemo with the lynparza at the same time.
So he will begin 4 cycles of combo chemo
cabazitaxel
+carboplatinum (taxane for the pc fellas and platinum for the neuroendocrine fellas). It would be to toxic for him to combine the chemo with the lynparza at the same time.
Bird8
in
Advanced Prostate Cancer
4 years ago
177Lu+225Ac or 177Lu?
He has had ADT, Provenge, was successfully on Abi+-ARN509 trial for 3 years, 10 cycles of docetaxel, treatment holiday, then restart of docetaxel but switch to
cabazitaxel
after 3 rounds due to progression in bone and lung. His last PSA rose to 48 from 41.
He has had ADT, Provenge, was successfully on Abi+-ARN509 trial for 3 years, 10 cycles of docetaxel, treatment holiday, then restart of docetaxel but switch to
cabazitaxel
after 3 rounds due to progression in bone and lung. His last PSA rose to 48 from 41.
Fullers19
in
Advanced Prostate Cancer
4 years ago
Why should I continue with ADT ?
I've had docetaxel,
cabazitaxel
, radiation (3) Xtandi, immunotherapy, parp inhibitor, etc Looking for answers from some of you smart guys out there. John
I've had docetaxel,
cabazitaxel
, radiation (3) Xtandi, immunotherapy, parp inhibitor, etc Looking for answers from some of you smart guys out there. John
Easey
in
Advanced Prostate Cancer
5 years ago
Cabazitaxel versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer
Cabazitaxel
was superior to switching to the alternate androgen-signaling inhibitor. Another brick in our wall of knowledge.
Cabazitaxel
versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer https://www.nejm.org/doi/full/10.1056/NEJMoa1911206?
Cabazitaxel
was superior to switching to the alternate androgen-signaling inhibitor. Another brick in our wall of knowledge.
Cabazitaxel
versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer https://www.nejm.org/doi/full/10.1056/NEJMoa1911206?
MateoBeach
in
Advanced Prostate Cancer
5 years ago
How long can I live with a PSA of 250
Have had ADT, Taxotere, Zytiga, Apalutamide,
Cabazitaxel
, & carboplatin Combo. My PSA got down to 3.9 and stayed there for one month and had been climbing for over a year. Looks like it is leveling off at 250 ish.
Have had ADT, Taxotere, Zytiga, Apalutamide,
Cabazitaxel
, & carboplatin Combo. My PSA got down to 3.9 and stayed there for one month and had been climbing for over a year. Looks like it is leveling off at 250 ish.
Raylin
in
Advanced Prostate Cancer
5 years ago
Cabazitaxel
Just wanted to ask if anyone has experience of having
cabazitaxel
and if so how did it go?
Just wanted to ask if anyone has experience of having
cabazitaxel
and if so how did it go?
Julie2233
in
SHARE Metastatic Breast Cancer
5 years ago
Survival With Cabazitaxel in Metastatic Castration-Resistant Prostate Cancer in Clinical Practice
TAKE-HOME MESSAGE •This cohort study was designed to evaluate real-world outcomes associated with the use of
cabazitaxel
for patients with metastatic castration-resistant prostate cancer. The median duration of treatment with
cabazitaxel
was 3.4 months.
TAKE-HOME MESSAGE •This cohort study was designed to evaluate real-world outcomes associated with the use of
cabazitaxel
for patients with metastatic castration-resistant prostate cancer. The median duration of treatment with
cabazitaxel
was 3.4 months.
Balsam01
in
Advanced Prostate Cancer
5 years ago
2019 Top Stories in Advanced Prostate Cancer: Cabazitaxel vs Abiraterone or Enzalutamide in Metastatic Prostate Cancer
There was improved tumor response with
cabazitaxel
; it was 37% in the
cabazitaxel
arm and 12% in the androgen signaling–targeted inhibitor arm (P=.004).
There was improved tumor response with
cabazitaxel
; it was 37% in the
cabazitaxel
arm and 12% in the androgen signaling–targeted inhibitor arm (P=.004).
Balsam01
in
Advanced Prostate Cancer
5 years ago
Round 7 Cabazitaxel incoming
Rounds 1 to 3 easy Round 4 lowered mobility Round 5 and 6 low days are day 4 to 10 Holiday season in January so looks like I will ask oncologist for a deferral of Round 8 to give me more energy to enjoy a family visit. PSA now over 500 , still on ADT. LDH over a thousand but hopefully not accelerating
Rounds 1 to 3 easy Round 4 lowered mobility Round 5 and 6 low days are day 4 to 10 Holiday season in January so looks like I will ask oncologist for a deferral of Round 8 to give me more energy to enjoy a family visit. PSA now over 500 , still on ADT. LDH over a thousand but hopefully not accelerating
GapBandTragic
in
Advanced Prostate Cancer
5 years ago
Anyone taking Darolutamide develope asthenia, a known side effect? I've read similar SEs with Xtandi, so is this with all lutamide drugs?
A wonderful oncologist in SC almost got him into that trial, but then he was rejected due to the one shot of Jevtana/
Cabazitaxel
he had!! Our MO said Darolutamide is almost the exact same as Proxalutamide, so we felt it was worth trying.
A wonderful oncologist in SC almost got him into that trial, but then he was rejected due to the one shot of Jevtana/
Cabazitaxel
he had!! Our MO said Darolutamide is almost the exact same as Proxalutamide, so we felt it was worth trying.
JLS1
in
Advanced Prostate Cancer
4 years ago
17 years with metastatic prostate cancer – hope disappearing down the Lu
I’ve decided against
Cabazitaxel
, as I don’t want to feel sick for months for no real gain. So, my fellow warriors, if you have any advice for future treatment, please let me know. I’m open to pretty much anything. Any advice will be gratefully received.
I’ve decided against
Cabazitaxel
, as I don’t want to feel sick for months for no real gain. So, my fellow warriors, if you have any advice for future treatment, please let me know. I’m open to pretty much anything. Any advice will be gratefully received.
Hidden
in
Advanced Prostate Cancer
5 years ago
Veyonda (idronoxil). For enhancing radiation effects and launching abscopal immune response. DARRT Trials and LuPIN Trial
LuPIN-1 trial of Veyonda with Lu-PSMA-617 in mCRPC (Australia) LuPIN-1 is a dose escalation and dose expansion trial of men with mCRPC progressing despite having received docetaxel,
cabazitaxel
and either abiraterone or enzalutamide.
LuPIN-1 trial of Veyonda with Lu-PSMA-617 in mCRPC (Australia) LuPIN-1 is a dose escalation and dose expansion trial of men with mCRPC progressing despite having received docetaxel,
cabazitaxel
and either abiraterone or enzalutamide.
MateoBeach
in
Advanced Prostate Cancer
5 years ago
Advanced prostate cancer
Hi im currently on
Cabazitaxel
haveing previosely been on docetaxel and im finding my psa keeps riseing and is now at 350 but for the last 2 years where my prostate has enlargened im haveing to self catheterise myself up to 6 times a day and im on off weeing with blood is anyone else out there haveing
Hi im currently on
Cabazitaxel
haveing previosely been on docetaxel and im finding my psa keeps riseing and is now at 350 but for the last 2 years where my prostate has enlargened im haveing to self catheterise myself up to 6 times a day and im on off weeing with blood is anyone else out there haveing
barlavington
in
Advanced Prostate Cancer
5 years ago
Liver metastasis
I've had stereotactic radiotherapy to the area before and looking at : RF ablation Chryotherapy SIRT BAT Starting
cabazitaxel
next week Any suggestions
I've had stereotactic radiotherapy to the area before and looking at : RF ablation Chryotherapy SIRT BAT Starting
cabazitaxel
next week Any suggestions
Easey
in
Advanced Prostate Cancer
5 years ago
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