Experiences with

Bortezomib

confirm if the great results that fast mimicking diet had in vivo can be obtained on humans as well, hopefully against prostate cancer :-P here is a "test drive" done on two patients with chronic leukemia https://aacrjournals.org/cancerres/article/84/7/1133/742051/Cyclic-Fasting-Mimicking-Diet-Plus-Bortezomib-and

Others, such as ectinascidin 743, chromomycin A3 and bortezomib utilized other mechanisms. Furthermore, many of these drugs induced caspase 3/7 activity and had an inhibitory effect on cervical cancer cell growth.

At the same time, because his multiple myeloma was also refractory to the initial chemotherapy of bortezomib, melphalan, and prednisolone (VMP), lenalidomide was introduced. His PSA level subsequently gradually decreased and remained low without any change in the CAB [Fig. ​[Fig.22]."

exacerbation of neuropathy in Charcot Marie Tooth Disease link http://cmt.org.uk/wp-content/uploads/2015/04/NeuroMeds.pdf Proposed list of medications of concern to patients with CMT Definite high risk (including asymptomatic CMT) Vinca alkaloids (vincristine) Moderate to significant risk Amiodarone Bortezomib

Anyway, cutting to the chase: "Apigenin selectively inhibits proteasomal degradation of tumor suppressor ER-β" "Unlike bortezomib, apigenin's actions are subtle, precise, mechanistically distinct and capable of abstaining drug resistance."

A third option for blood cancer patients, whose condition might not respond so well to the first two, was Bortezomib, which had a list price of $9742.

I started treatment with VAD chemo, but recently switched to Bortezomib and dexamethasone... Would be nice to read about similar MM journeys!

My system did not accept the velcade (bortezomib), and very early on I became pretty sick. Late February I told the doctor that I didn't want anymore chemo. He was hell-bent on the velcade but I insisted that I wanted no more of that stuff.