Search
Search
About
Log in
Join
Experiences with
Besremi
Posts
Communities
363 public posts
Filter results
Update 6.4
My plan at this point is to continue with the 110mcg dose of
Besremi
. If the HCT continues to creep up above 45%, then my plan is to bump the
Besremi
dose up to 125mcg and closely monitor my response. I will work in close collaboration with my MPN care team on this plan as needed.
My plan at this point is to continue with the 110mcg dose of
Besremi
. If the HCT continues to creep up above 45%, then my plan is to bump the
Besremi
dose up to 125mcg and closely monitor my response. I will work in close collaboration with my MPN care team on this plan as needed.
hunter5582
in
MPN Voice
2 years ago
Another Comparison of PEG to Besremi
I had this in a reply thread, figured it's worth its own. This recent report shows PEG and Bes are not the same in the context of Hep C. -- No way to say whether it's relevant to us, esp since Hep C treatment adds oral ribavirin, and it's a small trial. But it seems to show the two are good for Hep
I had this in a reply thread, figured it's worth its own. This recent report shows PEG and Bes are not the same in the context of Hep C. -- No way to say whether it's relevant to us, esp since Hep C treatment adds oral ribavirin, and it's a small trial. But it seems to show the two are good for Hep
EPguy
in
MPN Voice
2 years ago
Besremi vs Hydroxyurea
Also interesting is that
Besremi
is designed to treat the root cause of PV versus HU primarily treating downstream symptoms. https://www.youtube.com/watch?v=Kdu8suso21w
Also interesting is that
Besremi
is designed to treat the root cause of PV versus HU primarily treating downstream symptoms. https://www.youtube.com/watch?v=Kdu8suso21w
pepper-
in
MPN Voice
2 years ago
Want to take advantage of all our features? Just log in!
Log in
or
Join
Besremi shot #7
Hi everyone, 7th
Besremi
shot was last Friday and I did 125 mcg. I stayed at 100 mcg for about a month or more, but increased it a bit to avoid a phlebotomy as my iron levels are finally returning. Got CBC today. HCT was down a bit to 41.9 which means I can avoid getting phlebotomy...for now.
Hi everyone, 7th
Besremi
shot was last Friday and I did 125 mcg. I stayed at 100 mcg for about a month or more, but increased it a bit to avoid a phlebotomy as my iron levels are finally returning. Got CBC today. HCT was down a bit to 41.9 which means I can avoid getting phlebotomy...for now.
Elizka
in
MPN Voice
2 years ago
Anyone else experience worse side effects on Besremi as compared to Pegasys?
Anyone else feel better on Pegasys as compared to
Besremi
?
Anyone else feel better on Pegasys as compared to
Besremi
?
monarch5000
in
MPN Voice
2 years ago
Besremi doing well
« Sales of the drug are better than expected »
« Sales of the drug are better than expected »
Manouche
in
MPN Voice
2 years ago
Latest CBC CMP Besremi 3+ months
Just an update on current numbers as Bes continues. I wrote about eye concerns recently, and we shared many ideas there. Here is HCT. It's going the right way after some increase since the switch from HU. The larger dose I took last time (~110mcg) may have helped, but it was a wallop. I've had misc
Just an update on current numbers as Bes continues. I wrote about eye concerns recently, and we shared many ideas there. Here is HCT. It's going the right way after some increase since the switch from HU. The larger dose I took last time (~110mcg) may have helped, but it was a wallop. I've had misc
EPguy
in
MPN Voice
2 years ago
Besremi progress
I started a month ago. My fourth dose was last Wed. 1st three were at 50mcg, last one I did 70 as a compromise as I awaited Dr instructions. Next will be 100. The first week or two was harsh, max of my usual malaise, full headed etc. Likely this was from the HU combination thru the transition.
I started a month ago. My fourth dose was last Wed. 1st three were at 50mcg, last one I did 70 as a compromise as I awaited Dr instructions. Next will be 100. The first week or two was harsh, max of my usual malaise, full headed etc. Likely this was from the HU combination thru the transition.
EPguy
in
MPN Voice
2 years ago
A bit of drama on Besremi
.>>
Besremi
shares with Intron the -2b INF version. That 180 PEG is very high for MPNs, so more eye issues in this study might be expected. For weight/dose: I weigh 130lbs, US avg male is 200.
.>>
Besremi
shares with Intron the -2b INF version. That 180 PEG is very high for MPNs, so more eye issues in this study might be expected. For weight/dose: I weigh 130lbs, US avg male is 200.
EPguy
in
MPN Voice
2 years ago
DALIAH INF-HU trial new data analysis
This trial is a source to compare the main two INFs before
Besremi
came about. I believe they compared IFNα 2(a) Pegasys and IFNα 2(b) PegIntron. They don't go deep enough here to explain. The image here shows CHR for the two INFs and HU.
This trial is a source to compare the main two INFs before
Besremi
came about. I believe they compared IFNα 2(a) Pegasys and IFNα 2(b) PegIntron. They don't go deep enough here to explain. The image here shows CHR for the two INFs and HU.
EPguy
in
MPN Voice
2 years ago
Jakafi (Rux) vs Besremi Side Effects
The mean Bes dose for this effects table was 334mcg, more than anyone here has reported taking so far. -- Table 2 in https://www.rxlist.com/
besremi
-side-effects-drug-center.htm and table 13-14 in https://www.rxlist.com/jakafi-drug.htm#side_effects
The mean Bes dose for this effects table was 334mcg, more than anyone here has reported taking so far. -- Table 2 in https://www.rxlist.com/
besremi
-side-effects-drug-center.htm and table 13-14 in https://www.rxlist.com/jakafi-drug.htm#side_effects
EPguy
in
MPN Voice
2 years ago
Omega 3's to reduce some MPN issues?
This and taking more Magnesium Glycinate, Meriva 500SF, and Feverfew have helped reduce the frequency of my migraines which have increased due to
Besremi
.
This and taking more Magnesium Glycinate, Meriva 500SF, and Feverfew have helped reduce the frequency of my migraines which have increased due to
Besremi
.
Elizka
in
MPN Voice
2 years ago
BESREMi 4th dose
From the appointment before
BESREMi
, 1/19/22: HCT 35.4 / RBC 4.07 / WBC 5.4 / Platelets 222 After 1 dose
BESREMi
, right before 2nd dose, 2/25/22: HCT 37.2 / RBC 4.22 / WBC 6 / Platelets 255 After 3 doses
BESREMi
, right before 4th dose, 3/24/22: HCT 34.9 / RBC 3.92 / WBC 4.7 / Platelets 204 A far cry
From the appointment before
BESREMi
, 1/19/22: HCT 35.4 / RBC 4.07 / WBC 5.4 / Platelets 222 After 1 dose
BESREMi
, right before 2nd dose, 2/25/22: HCT 37.2 / RBC 4.22 / WBC 6 / Platelets 255 After 3 doses
BESREMi
, right before 4th dose, 3/24/22: HCT 34.9 / RBC 3.92 / WBC 4.7 / Platelets 204 A far cry
lynxfluff
in
MPN Voice
2 years ago
Latest CBC, CMP and Besremi shot
I had my 5th shot last week. It was at 100mcg, next will be at 150. I had a [i]very[/i] bad day yesterday. It felt like an Omicron infection (runny nose, headache, slight sore throat, misc discomforts) along with a big dose of the usual malaise. But I wear a good fitting N95 always on my rare outings
I had my 5th shot last week. It was at 100mcg, next will be at 150. I had a [i]very[/i] bad day yesterday. It felt like an Omicron infection (runny nose, headache, slight sore throat, misc discomforts) along with a big dose of the usual malaise. But I wear a good fitting N95 always on my rare outings
EPguy
in
MPN Voice
2 years ago
Migraines and Besremi?
This is a MPN Community but I thought sharing my experience with migraines that could be/(who knows) related to
Besremi
would help someone.
This is a MPN Community but I thought sharing my experience with migraines that could be/(who knows) related to
Besremi
would help someone.
Elizka
in
MPN Voice
2 years ago
Defining INF effectiveness
With many of us starting
Besremi
, there is discussion of what dose we are or will be getting. As noted by member mfh7 the clinical studies for Ropeg (
Besremi
) used dosings of 500mcg.
With many of us starting
Besremi
, there is discussion of what dose we are or will be getting. As noted by member mfh7 the clinical studies for Ropeg (
Besremi
) used dosings of 500mcg.
EPguy
in
MPN Voice
2 years ago
Update 6.3 - Good News
https://www.besremi.com/pdf/
BESREMI
-travel-letter.pdf All of the best to all of you all.
https://www.besremi.com/pdf/
BESREMI
-travel-letter.pdf All of the best to all of you all.
hunter5582
in
MPN Voice
2 years ago
9 weeks on Besremi: Update
Not thrilled if I'm taking
Besremi
and still need to get phlebotomies, but time will tell. Side effects: I've had a few days where I felt like a zombie in the afternoons. I have had that before so maybe PV? Or maybe, age-related? Who knows.
Not thrilled if I'm taking
Besremi
and still need to get phlebotomies, but time will tell. Side effects: I've had a few days where I felt like a zombie in the afternoons. I have had that before so maybe PV? Or maybe, age-related? Who knows.
Elizka
in
MPN Voice
2 years ago
Peg-Interferon therapy, contraindications
I have read several posts about the positive experience from peg-ifn therapy (whether Pegasys or, more recently,
Besremi
) , as more of us MPN'ers are switching to these biologics.
I have read several posts about the positive experience from peg-ifn therapy (whether Pegasys or, more recently,
Besremi
) , as more of us MPN'ers are switching to these biologics.
Aldebaran25
in
MPN Voice
2 years ago
Besremi -Six Week Update
Background: I got my first
Besremi
shot on January 28. I asked to start at 50 mcg. Second shot was 60 mcg and third was 70mcg.
Background: I got my first
Besremi
shot on January 28. I asked to start at 50 mcg. Second shot was 60 mcg and third was 70mcg.
Elizka
in
MPN Voice
2 years ago
1
...
14
15
16
...
19
Next page
10
Filter results
Clear filters
Posted in
All communities
MPN Voice
361 results
Fight MPN
2 results
Sort by
Most Relevant
Newest