Experiences with

Azacitidine

It never needed to escalate to the level it did if he had explained that Claire Harrison at a big London hospital can access Azacitidine but at provincial hospitals it is not readily available The results of my BMB showed additionally acquired mutations ( I’ll let you know exactly what when I get

It is not reducing, so my Haematologist recommended a chemo drug named Azacitidine. I have had the first cycle of 7 days and finished just over a week ago. However, I am experiencing Insomnia. I cannot sleep and have no desire to sleep.

Hello everybody Haven’t been on fo a while as I feel I can’t help much 6years ago I was diagnosed with ET and for 3years this went along nicely with HU and aspirin then I very suddenly progressed to MDS and put on anagrelide to no avail then Rux also to no avail and the Azacitidine to no avail I then

After having been on Azacitidine for over 3 years, a couple of weeks ago my doctor added Venclexta with a short ramp-up .. 100mg..200mg..300mg..400mg. I am very curious about the experience people have had with this combination. How fast did you see results? Have there been any side effects?

Had another maintenance round of azacitidine, followed by another blood test to check if still all good. Saw my haematologist yesterday here in Jaen, Spain and he said how pleased he was with my results. Except for my platelets (down), bloods are near to normal as they can be.

Because of my age (74), I am on azacitidine injections, plus thioguanine tablets. Delay further treatment a week for another blood test, to see if any improvement in my WBC, if not may bring forward my biopsy to check what my bone marrow is doing.

Sounds very encouraging http://www.bloodjournal.org/content/132/16/1664

anyone had Ruxo with Azacitidine? I have high risk MF which is unstable and tending towards AMF. Azacitidine sounds unpleasant and I'm not convinced that it's worth it.

I do have some side effects - arms ache for about 10 to 15 days after having the Azacitidine injections and my spine/shoulder blades ache. I do get tired some days. Most days I feel great.

DNA methyltransferases (DNMTs) constitute the group of enzymes responsible for maintaining these CpG methylation marks, and have been the primary target of drugs developed as demethylating agents.1 Two nucleoside DNMT inhibitors, azacitidine and decitabine, are currently approved for the treatment of