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goserelin and ACTH
I am wondering how and if GnRH medications like Zoladex impact the ACTH production and if the activity of the adrenal production of adrenal androgens feeds the prostate cancer cells independently of the LH / testosterone route. Also as cortisol is increased with various other physical and psychological
I am wondering how and if GnRH medications like Zoladex impact the ACTH production and if the activity of the adrenal production of adrenal androgens feeds the prostate cancer cells independently of the LH / testosterone route. Also as cortisol is increased with various other physical and psychological
SimMartin
in
Prostate Cancer Network
21 days ago
Thyroid and cortisol results
Hi all, just got results back from latest NHS bloods. Any thoughts? This was primarily to try and 'verify' my private blood test results showing above-range TSH (6.1) and high antibodies. Test was done just before 9am, fasting, currently not on any meds, no biotin week before. I also asked for serum
Hi all, just got results back from latest NHS bloods. Any thoughts? This was primarily to try and 'verify' my private blood test results showing above-range TSH (6.1) and high antibodies. Test was done just before 9am, fasting, currently not on any meds, no biotin week before. I also asked for serum
seveneleven
in
Thyroid UK
1 month ago
More advice please!
Hi All - Thanks for all who responded to my post here - https://healthunlocked.com/thyroiduk/posts/149317400/still-struggling-... I do think my next step is to investigate/test vitamin D, folate, B12, and ferritin. This is not an aspect that I know much about, so I have various questions. A very
Hi All - Thanks for all who responded to my post here - https://healthunlocked.com/thyroiduk/posts/149317400/still-struggling-... I do think my next step is to investigate/test vitamin D, folate, B12, and ferritin. This is not an aspect that I know much about, so I have various questions. A very
UKmale_hypo
in
Thyroid UK
2 months ago
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Update #5: Back to front
Hi all, Continuing on from my adrenals results… https://healthunlocked.com/thyroiduk/posts/149321002/update-4-adrenal-results I have spent some time researching and experimenting with adrenal support. This is what I understand. If I am off about any of this please do feel free to correct or challenge
Hi all, Continuing on from my adrenals results… https://healthunlocked.com/thyroiduk/posts/149321002/update-4-adrenal-results I have spent some time researching and experimenting with adrenal support. This is what I understand. If I am off about any of this please do feel free to correct or challenge
dontforgetcortisol
in
Thyroid UK
2 months ago
Adrenal Insufficiency treatment?
Hello, I wrote a post last week when I got a major GCA headache and felt incredibly weak and was having difficulty talking, finding words. I increased my prednisone from 9mg to 15mg three days ago but still feel very weak, fatigued, and major brain fog. Someone on here used the term "walking with someone
Hello, I wrote a post last week when I got a major GCA headache and felt incredibly weak and was having difficulty talking, finding words. I increased my prednisone from 9mg to 15mg three days ago but still feel very weak, fatigued, and major brain fog. Someone on here used the term "walking with someone
potterylady
in
PMRGCAuk
2 months ago
Update #4: Adrenal Results
Strangely enough, my results are back. I spoke with the endo this evening who gave me his take. He thinks I have primary adrenal insufficiency, he believes this because my endogenous ACTH is suffice according to him. He sees my Aldosterone & Cortisol are both lacking and stated this is why my thyroid
Strangely enough, my results are back. I spoke with the endo this evening who gave me his take. He thinks I have primary adrenal insufficiency, he believes this because my endogenous ACTH is suffice according to him. He sees my Aldosterone & Cortisol are both lacking and stated this is why my thyroid
dontforgetcortisol
in
Thyroid UK
2 months ago
Adrenals are working!
I had a ACTH Stimulation Test this morning and just got the results back from my Endo. She said even better than she expected. So now I can start tapering off of hydrocortisone at 1/2 tablet weekly. Currently I am on two 5mg tablets in morning and Two 5mg tablets in evening. It seems a bit fast but
I had a ACTH Stimulation Test this morning and just got the results back from my Endo. She said even better than she expected. So now I can start tapering off of hydrocortisone at 1/2 tablet weekly. Currently I am on two 5mg tablets in morning and Two 5mg tablets in evening. It seems a bit fast but
pmac22
in
PMRGCAuk
3 months ago
ACTH results - please see my previous post
Please see my previous post. I am particularly interested to know what ACTH *15 (Roche Method) indicates? Thank you Jane :)
Please see my previous post. I am particularly interested to know what ACTH *15 (Roche Method) indicates? Thank you Jane :)
smilingjane
in
Thyroid UK
3 months ago
ACTH Cortisol test enquiry
Afternoon all I had an ACTH test done at the request of my GP because my early morning blood cortisol test was 133 (ref 113 - 532). I am attaching 2 pages of results. The consultant says I'm fine but I want to run it past folk on here because I'm not so sure. I certainly don't feel fine. I don't understand
Afternoon all I had an ACTH test done at the request of my GP because my early morning blood cortisol test was 133 (ref 113 - 532). I am attaching 2 pages of results. The consultant says I'm fine but I want to run it past folk on here because I'm not so sure. I certainly don't feel fine. I don't understand
smilingjane
in
Thyroid UK
3 months ago
Adrenal and related Test Results help please
I had the full bells and whistles blood screen by an NHS endo last year. I was sent a letter telling me I’m ‘healthy’ but I sure don’t feel that way. Some of the test results are below and I’d welcome any feedback. I’m 60 years old and post menopausal, I was medication free when the tests were done.
I had the full bells and whistles blood screen by an NHS endo last year. I was sent a letter telling me I’m ‘healthy’ but I sure don’t feel that way. Some of the test results are below and I’d welcome any feedback. I’m 60 years old and post menopausal, I was medication free when the tests were done.
Jamima
in
Thyroid UK
3 months ago
#2 Update: Adrenal Testing
This afternoon (12.45) I had the blood draw for: Adrenal auto-antibodies, Aldosterone, Renin, Potassium & Sodium. I've also had a short Synacthen test. Stop The Thyroid Madness (For better, for worse) insist that salt is restricted the day before Aldosterone testing and that the arm is held at a perpendicular
This afternoon (12.45) I had the blood draw for: Adrenal auto-antibodies, Aldosterone, Renin, Potassium & Sodium. I've also had a short Synacthen test. Stop The Thyroid Madness (For better, for worse) insist that salt is restricted the day before Aldosterone testing and that the arm is held at a perpendicular
dontforgetcortisol
in
Thyroid UK
3 months ago
Tsh 31,atrophied thyroid, secondary adrenal insuffiency , feel terrible in a maze, can't rise t3
Dear group, firstly, thankyou to be there! My name is Antonella, I write from Italy. I have secondary adrenal insuffiency due pituitary acth deficiency. I also have a genetic liver illness which make me very difficult metabolize and use every meds, supplements etc. Because of this, despite high dose
Dear group, firstly, thankyou to be there! My name is Antonella, I write from Italy. I have secondary adrenal insuffiency due pituitary acth deficiency. I also have a genetic liver illness which make me very difficult metabolize and use every meds, supplements etc. Because of this, despite high dose
flyngraft
in
Thyroid UK
3 months ago
saw article linked https://healthunlocked.com/thyroiduk/posts/private/149179395/t3....again
https://healthunlocked.com/thyroiduk/posts/private/149179395/t3....again is this is what is happening to me ? My tsh before starting T3 was 0.02 and t4 20 (12 to 22) and T3 2.1 ! (4.1 to 6.8) and the past 3 days have swollen up like a balloon and fat gain on legs it’s insane I saw my gastro doctor
https://healthunlocked.com/thyroiduk/posts/private/149179395/t3....again is this is what is happening to me ? My tsh before starting T3 was 0.02 and t4 20 (12 to 22) and T3 2.1 ! (4.1 to 6.8) and the past 3 days have swollen up like a balloon and fat gain on legs it’s insane I saw my gastro doctor
Chouchou1234
in
Thyroid UK
3 months ago
ACTH blood test
My GP has sent me for an ACTH blood test. Is this the correct test or should he have asked for ACTH Stimulation test? Will the ACTH test be sufficient? I am almost at 3.5mg Pred. To be fair, I asked if I needed an ACTH test - I didn't realise there were two. But surely he knows what is needed?
My GP has sent me for an ACTH blood test. Is this the correct test or should he have asked for ACTH Stimulation test? Will the ACTH test be sufficient? I am almost at 3.5mg Pred. To be fair, I asked if I needed an ACTH test - I didn't realise there were two. But surely he knows what is needed?
ChinaWuntoo
in
PMRGCAuk
4 months ago
Substitute Eplerenone for Prednisone with Zytiga?
I am taking Eligard + Zytiga + Prednisone (5mg). I would like to stop the prednisone and substitute eplerenone (Inspra), if that is viable. I found this exchange from earlier this year from Gearhead, with comments from Tango65 and T_A, among others. Has anyone stopped prednisone altogether in
I am taking Eligard + Zytiga + Prednisone (5mg). I would like to stop the prednisone and substitute eplerenone (Inspra), if that is viable. I found this exchange from earlier this year from Gearhead, with comments from Tango65 and T_A, among others. Has anyone stopped prednisone altogether in
garyjp9
in
Advanced Prostate Cancer
5 months ago
Adrenal Insufficiency???
Hello everyone, this nightmare journey just seems to be never ending and I am so in need of some advice....... 8 days ago I took my last 1mg of Prednisone after being on it for 12 months starting at 65mg plus weekly Actemra injections. It seems that I have done well being able to get off Pred after
Hello everyone, this nightmare journey just seems to be never ending and I am so in need of some advice....... 8 days ago I took my last 1mg of Prednisone after being on it for 12 months starting at 65mg plus weekly Actemra injections. It seems that I have done well being able to get off Pred after
MarksPoint
in
PMRGCAuk
6 months ago
THE HPA AXIS OR THE TRIO.
The following is a long post and you may want to copy it or put in your Saved Posts. It was published in a Newsletter (which is now defunct) and written by PMRpro, this time I actually asked if I could post it on here. The explanation has been written in language that we can all understand,medical
The following is a long post and you may want to copy it or put in your Saved Posts. It was published in a Newsletter (which is now defunct) and written by PMRpro, this time I actually asked if I could post it on here. The explanation has been written in language that we can all understand,medical
jinasc
in
PMRGCAuk
6 months ago
Self medicating hydrocortisone
TSH - 0.93 (0.23-5.6) ft4 - 12 (9-28) ft3 - 4.4 (3.1-6.8) acth - 19.8 (7.2-63.3) Testosterone 0.2 (0.3-1.7) Blood Cortisol -10.30am SST- 216 rising to 611 after synacthen injection I've consulted 2 endos within the past couple of months, I've outlined very clearly the symptoms I have and how they
TSH - 0.93 (0.23-5.6) ft4 - 12 (9-28) ft3 - 4.4 (3.1-6.8) acth - 19.8 (7.2-63.3) Testosterone 0.2 (0.3-1.7) Blood Cortisol -10.30am SST- 216 rising to 611 after synacthen injection I've consulted 2 endos within the past couple of months, I've outlined very clearly the symptoms I have and how they
Jamima
in
Thyroid UK
7 months ago
Advice on ACTH and thyroid results please
I had a '2nd opinion' visit to an NHS endo on 24/8/22. I specifically asked the endo to comprehensively test my pituitary function, as I think that's where my problems are located (low thyroid and cortisol). She did a lot of blood tests and an ACTH test. After a fair bit of chasing up I've now been copied
I had a '2nd opinion' visit to an NHS endo on 24/8/22. I specifically asked the endo to comprehensively test my pituitary function, as I think that's where my problems are located (low thyroid and cortisol). She did a lot of blood tests and an ACTH test. After a fair bit of chasing up I've now been copied
Jamima
in
Thyroid UK
8 months ago
ACTH Stim Test Results
Hello. I've had PMR for 1 1/2 years and started at 40 mg Pred now down to 2 mg. It's been a struggle to get down and am still much fatigued , so based on blood test results below my doc ordered the cortisol/ACTH stim blood test. Results: 6 mos ago am on 5 mg Pred adrenocorticopnophic (sp?)result
Hello. I've had PMR for 1 1/2 years and started at 40 mg Pred now down to 2 mg. It's been a struggle to get down and am still much fatigued , so based on blood test results below my doc ordered the cortisol/ACTH stim blood test. Results: 6 mos ago am on 5 mg Pred adrenocorticopnophic (sp?)result
kp60
in
PMRGCAuk
8 months ago
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