Colchicine and SARS-CoV-2: Management of the hyperinflammatory state

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Colchicine and SARS-CoV-2: Management of the hyperinflammatory state, Feb 2021.

"Colchicine is a pharmacological agent that has been used for a long time and with different therapeutic indications. Today it is used effectively in the treatment of gout, Behçet's disease, for the prevention of pericarditis, Familial Mediterranean Fever (FMF), Sweet's syndrome."

"Evidence has shown that reducing or stopping the hyperinflammatory state that occurs in some infected patients COVID-19 is effective in improving health. The use of colchicine, as well as its proven efficacy in the prophylaxis and treatment of autoinflammatory diseases such as FMF or pericarditis, could be considered in all three stages of SARS-CoV-2 infection, especially in those patients at high risk of developing serious lung complications in a dramatically short time, in monotherapy or in combination, carefully monitoring possible drug interactions." ncbi.nlm.nih.gov/pmc/articl...