I am struggling with secondary Reynaud's (undifferentiated connective tissue disease) and my fingers/hands are swelling so badly during flares and are causing me terrible pain. It does not seem to be related to cold weather conditions as I get it during warmer weather too. I am on Hydroxychloroquine but have been unable to tolerate Losartan or nifedipine tablets. The consultant has suggested a 5 day Iloprost infusion via IV. Has anybody else had this and if so was it effective? Were there many side effects? Many thanks.