Do any of you take longer than 1 week off? Like maybe take 9-10 days off? I would really like to do this once in a while because I think it would help my blood cells to recover more. My doctor isn't really in favor of this but I was just wondering if any of you do this on your own.
Ibrance schedule: Do any of you take... - SHARE Metastatic ...
Ibrance schedule
My NP, with permission from my oncologist, put me on a 3 week on and 3 week off routine of Ibrance.
My WBC’s take 3 weeks to come back to normal before starting a new cycle. I’ve been on this schedule for the last 3+ years and my regular CT scans show stable each 3 months.
I’ve been on Ibrance 100mg since October, 2019, having dropped from 125mg when WBC’s dangerously low.
I hope this helps and I wish you all the best on your treatment. Hugs, KS
With my oncologist's support, I take ribociclib on my own schedule which is weekdays on, weekends off. This schedule keeps my cancer antigens in the normal range so they are not growing ( I have breast cancer in many sites).
Most importantly, my leukocycte count stays well above the very low level (below 1) where it was on a three weeks on, one week off schedule. It is still not in the normal range (it's currently 2.7, not the Canadian standard of 4.1+) but at least I have some protection from infection.
Please note that weekends off mean I take ribociclib (with letrozole) on 20 days every 28 days. On a three weeks on, one week off schedule, I would be taking meds on 21 days every 28 days. We're really only talking about 1/28th less!
Thanks for sharing. My numbers have never been extremely low; but they just always stay low, no matter where I am in the cycle. My oncologist isn't concerned about it. I just want my numbers higher once in a while!
I am currently on a three week on two week off schedule, 125 mg dose. I never totally recover to a normal wbc and anc, but it has been stable for a few years now, no low dips. My oncologist is very by the book and generally follows what is recommended. After two or three times that I had to wait another week this became my schedule. Pfizer has recommendations about when Ibrance should be held according to neutrophil levels. Maybe you can use these to discuss with your oncologist.
Thanks for your reply. My levels have never been super low. But they don't ever seem to be anywhere near the normal level. They just seem to stay low no matter where I am in the cycle. That's why I wanted to give it a little more time to see if they would come up more. Thanks again! How long have you been on Ibrance?
I regularly take 8 days off as I know 7 days is not enough to get neutrophils up to 1.00. I have been on this combo (palbo and letrozole) for 6 years and am on 75mg. Hope that is some help. I have not told my oncologist I am doing this !
guess I could stop pill earlier
I took an extra week at one point, but it was recommended by my oncologist/