Can anyone share side effects with Capecitabine and Eribulin?

[MONICAGELLER409]

I have MBC which is progressing and I have to make a choice between these two treatments. I would really appreciate hearing from you the different side effects. It is so difficult to make a choice. Thanks!!!!

[Sweeten_1]

I'm my 4th month of capecitabine or xeloda and feel good. Some mets are gone in bones and tm down to 30. Stopped intestinal and diarrhea. Only side effect was hand foot syndrome the 3rd round and onc put me 1 wk on and week off. 3,000 mg a day. I had been on ibrance and faslodex. Still get zometa every 12 wks. Diagnosed from start in dec 2012. Onc said she has had women on xeloda for several years good results. I don't know anything about other drug. I have alot of energy feel good😊

[MMMP in reply to Sweeten_1]

My concern is what to take when the xeloda stops working!!

[MONICAGELLER409 in reply to Sweeten_1]

Thank you for letting me know. I am currently on ibrance and palbo but it’s not working and the disease is progressing. I have to make a decision soon and so I thought i would come for some help here. I appreciate you taking the time to let me know your experience.

[My3girls]

I've been on xeloda or capecitabine for 4 cycles now and I'm feeling pretty good. I just get pretty tired at the end of the cycle and my hand and feet are a little swollen and sore. So far the hardest part has been remembering to take it twice a day. Best of luck to you!

[MMMP in reply to My3girls]

I take it following my breakfast and than again following my evening meal- I need to take with food in stomach- usually wash it down with a beer in the evening!

[Clair19 in reply to MMMP]

To funny 😆! I love beer 🍺.

[MONICAGELLER409 in reply to My3girls]

I’m so happy to hear that both you and MMMP are tolerating it well. Makes me hopeful that i will be able to handle it too. I refuse to take anything than will destroy my quality of life. Whatever time i have left, I choose to not spend it laid up on a bed.

[MMMP]

I've been on xeloda for over 2 years 3000 mg 7 days on 7 days off. Take 1500 twice a day- started off on the xeloda too high at 4000mg for 2 weeks on and 1 week off- than switched-I suffer from the hand and foot syndrome- no issues with GI - it's expensive but once I paid for the first month it was covered - this is the only med I have been on since it had spread to my bones. Triple negative so not much out there. I did research the other med- interesting but saw hair loss as a side effect- no thanks already lost it 3 years ago and not going back there- good luck -

[MONICAGELLER409 in reply to MMMP]

Yes, I lost mine too and have no desire to live life with cancer and bald to boot! Once was wnough for me 😊

[mm27]

Been on xeloda since January of this year after progression with Ibrance and Letrozole. Taking 1000 mg twice a day and have not experienced any of the horrible side effects was warned about. Feel tired and gained weight but don't know if that's the medicine. Tumor markers have come down to normal levels and recent ct scan shows" significant improvement". Hopeful that improvement will continue. Good luck with your decision. I sure you and your doctor will make the best possible choice.

[MONICAGELLER409 in reply to mm27]

Hi MM, Happy Friday! Thank you so much for sharing your experience with xeloda. I was petrified about taking it but from what I’ve been hearing from all you lovely ladies in this community, I’m feeling less fearful and more and more hopeful that it will help lower my markers too. Doc told me to moisturize a lot so I don’t get hand/feet syndrome. Do you use any particular moisturizer? Thanks for the support 😊

[JBirdnut]

On Ibrance until yesterday. Recent PET SCAN showed progression in my spine and now in the sacrum. My Onc wants me on Eribulin. It is an infusion drug, so I have to get a port put back in, ugh.

He said for his patients that Ibrance fails on, he likes Eribulin. Says he gets very good results. Infusion on day one and eight only of a 21 day cycle. List of side effects are the usual with hair loss being at the bottom of the list..... I hope that means something!

Any one else out there on Eribulin?

I had great hope with Ibrance. Down in the dumps right now, but will be up for the fight soon! Just have to grieve for a day or two.

Best wishes to all going through this hell.

Janine in SE Louisiana

[MONICAGELLER409 in reply to JBirdnut]

I’m sorry to hear ibrance didn’t work. You should definitely allow yourself to mourn. It helps us feel stronger afterwards for our fight. Sending you good vibes for success and very fee side effects.

[Juliandrea in reply to JBirdnut]

I Janine, sorry ibrance didn’t work for you, how long were you on it? I am sure the new treatment will work for you, stay strong. You probably have made a choice by now. Keep us updated. Thank you for being such an inspiration to us all.

[JBirdnut in reply to Juliandrea]

Hi again. I started Ibrance on Jan 1st of this year. After 3 mos, PS showed significant improvement. Spot on liver was gone and the 3 bone lesions were smaller with evidence of bone growth. I was elated! About a month ago, back pain started again. My 6 month PS done last week showed more progression in the spine and into the sacrum and an "undetermined"spot on adrenal gland that Onc said is a concern.

I have many prayer warriors helping me through this and great family and friends.

My passion is birdwatching which takes me away from all my worries.

Great mind and body therapy.

Best to all

Janine in SE Louisiana

[Clair19 in reply to JBirdnut]

Yes it’s pure hell I will agree to that. I took Chemo and it was just existing and that’s no way to live. So I will pray that mine stays stable for now. If it’s just in your bones can’t they give you a bone bonding medicine? I was just wondering if it’s any place else? Thanks 🙏

[Juliandrea]

Thank you for your reply, are you on a new treatment yet?

[MONICAGELLER409 in reply to Juliandrea]

I opted for xeloda but can’t start yet as my white cells are too low. I start next Friday. Today i got my xgeva and i feel drained. Every time i get that shot i feel like dead weight. All i do is sleep. They need to come up with a cancer med that has the side effect of happiness!

[Clair19 in reply to MONICAGELLER409]

I can’t take Xgeva, made me so sick I thought I was going to die. I’m just trying Faslodex for now which is easier for my body to handle. I wish you luck on your new medication.

[MONICAGELLER409 in reply to Clair19]

Oh Clair i know the feeling! It’s brutal on the body. If it’s too much when i start oral chemo i will request it quarterly. Monthly is rough!

[JBirdnut in reply to Juliandrea]

No, not yet. I have to meet with the General surgeon who will implant the port. So, probably won't get first treatment for about 2 weeks from now.

The shock, sadness and anger have subsided. I am thinking this just might work for me with less side effects..maybe keep my hair!🤗

[Clair19 in reply to JBirdnut]

How long did you have your port? I’m getting mine taken out on the 16th. Was it painful taking it out?

[JBirdnut]

Best wishes with the Xeloda.

I get the Xgeva injection also, once every 3 months. Have not noticed any increase in fatigue. Yes, why can't the researchers add a "happy" protein to our meds!

Best,

Janine in SE Louisiana

[MONICAGELLER409 in reply to JBirdnut]

Thanks Janine! Hopefully we will both get through these changes with minor downsides. Talk soon. Enjoy your weekend!

[Melpub]

I had a choice between capacetabine and a mix of exemestate and evrolimus. I took the capacetabline and had very bad hand/foot syndrome--feet really red and felt like they were burning (needed bag of ice and a steroid cream). But I used my feet a lot--tap dance and walking and the gym. Then it turned out the capacetabline wasn't working anyway. But I may not be typical--many women seem to do fine on capacetabine. I had no problems with Ibrance and Faslodex, which I'd been on for 4.5 years (and some have problems with these). So I think these things are very individual. Now I'm on Avastin and Paclitaxel, which I find exhausting, and trying to get my insurance co to pay for Enhertu.