What is the maxi dose of Ropinerole safe to take.

[kimpusan]

[Hidden]

I dont use Ropinerole, but the highest dose for RLS is 4mg. Anything above that dose usually means that after a while the RLS will come back worse than ever... its called augmentation...

[kimpusan in reply to Hidden]

Thank you Elisse for your answer, I am reluctant to increase my dose as my arms and legs get that awful ache more often now ,should I ask my Doctor to give me alternative to Ropinerole.

[Hidden]

If your symptoms are getting worse, then it sounds as if you need to change meds... Best to discuss it with your doctor...

[nightdancer]

What dose are you on now? If you are at 4 mgs, and it is not working for you any more, then it is time to talk to your doctor and change meds.

[dekker]

Up to a couple of years ago the maximum dose of Ropinirol was 4 mg. Nowadays however, the RLS experts who treat lots of RLS patients and have seen the augmentation problem getting worse their advice is not to exceed 1 mg, which is quite low. Of course they have patients on a higher doses, but this is what they recommend now.

[nightdancer]

Yes, the longer a drug is out, the more we learn about it. I have always felt the 4 mg per day dose was too high for RLS. I see people developing augmantation after only being on Ropinerole for a few wks, and at a 1 mg dose, so you never know. I do know that almost anyone in my support groups that has taken Ropinerole do develop augmentation. mirapexin is in the same class of emds, it s stronger, so lower doses. Good and bad with this- Mirapex can cause augmentation also plus the FDS just put a new warning out about Miraex and cases of heart failure. Not BIG numbers, but it the study followed thousands of people over a 6 yr period. Ther ARE other meds to be taken.

[nightdancer]

Neupro patch is the same class of meds, but is time released over 24 hrs, and has lower incidents of augmentation. Less of the nauseating side effects, too, for most who have or are trying it.

[Avosyl]

I have over the years tried a few things but found the Ropinirole was the only med to do any good. However lately things are not so good and after reading all the talk of augmentation i have asked my GP to refer me back to a consultant. I am in fact on 8mg three times a day which according to one consultant who deals in Parkinsons is the max which he didnt see as a problem. That was before i found this site. Now i am getting worried after reading that 4mg a DAY is the max. My GP put me on the Neupro patch (lowest dose) and i went through a day of pure hell. Not sure what to do now. I have RLS which runs in the family and it took me a lot of years to get a doc to listen and take me seriously. I got a lot of relief from Ropinirole for a long time but now i am suffering episodes (especially when damp or raining) that 'get through' and cause really bad times especially when my arms start to go at the same time.The dose i am on now has built up over approx ten years or more. I do not want to go on the likes of Amatryptaline as i spent years on those for depression resulting in a massive weight gain which i am only now getting rid off. I have various other health problems where extra weight makes it worse so dont want to visit that again ever. I would be grateful for any feedback on this. As i say i am waiting for an appointment with the consultant again but not sure how long this is going to take.

[cefndaniel in reply to Avosyl]

Hi

You are the first person who has said the weather has an effect on your RLS. When it rains and is damp I suffer a lot more. Another strange thing is that my ears become very itchy just before the legs start. This is the first time I have mentioned this excert to my GP who laughed!!!!!!!!!! I take 2mg of Ropinorole and one Tremadol. Recently after reaching augmantation I strugged to cut down the Ropinorole to 1 mg for a month and then started back on 2 mg and the augmentation stopped.

[Avosyl in reply to cefndaniel]

Thank you for that. In fact your the first to agree about the weather. i dread the winter months in particular and when i mentioned the same thing to my sister the other week she remembers that when i was younger i could always tell her when it was going to rain lol. People including my own family looked at me as if i was nuts at the time. How on earth did you manage to cut down on the Ropinirole. I have tried Tramadol before but it did absolutely nothing for me and i know i am on way too high a dose of the Ropinirole which is why i asked for a ref back to the consultant. What is the highest dose you have taken and how did the augmentation show in you. Its really driving me nuts now but there have been occasions where due to stomach bugs the effects of any meds has been lost and i have struggled not to bang my head against a brick wall and walked around my flat in tears ranting and raving at the agony of it. Do you have family help and back up? Do they understand how it affects you. Although most of my family seem to suffer to some degree of RLS i seem to have taken on the worst of it right from the beginning starting well before any of the rest and basically trying to advise them as to the next leg of the problem.