Hi all. I've been on 3mg/24 hours Neupro dermal patches for a few months now. I fear that the effect (24 hour relief from RLS in the main) is beginning to wear off. I also wonder if my extreme tiredness could be a side effect of using them. In an attempt to stop the kicking and get some sleep, I'm commonly boosting an evening usage with one or two 0.088mg Mirapexine tabs but don't know if that's a wise thing to do or not (it works). I'm considering asking my GP for 4mg/24 hours patches, which is the low dosage for treating Parkinson's Disease. Worrying really but have any of you tried 4mg Neupro patches and have they worked for you? All the best, Tpebop.