Trazodone and Gabapentin

[zeusop]

I am a bit of pharmophobe so I try to keep drugs and doses to a minimum. My RLS is not severe although it is there and only in the evenings. I have found that 50 mgs Trazadone and 100 mgs Gabapentin however taken before bed has helped me sleep enormously. Is there a danger in taking them together? As far as the RLS it seems to worse around bedtime which does make me get out of bed a couple of times but the sleep has improved.

[SueJohnson]

There is no danger in taking them together, But 100 mg is lower than the starting dose of gabapentin, so you could certainly increase it by 100 mg every couple of days until you find the dose that works for you. Are you off ropinirole?

[zeusop in reply to SueJohnson]

Yes absolutely. Thank you for your help!!

[grassgree]

Gabapentin usually helps with sleep quality, even at doses lower than needed to control RLS. If 100 mgs is working for you, I'm not sure why you should increase it. Every drug has a down side.

[Guitarpickin in reply to grassgree]

Yes, I agree completely. And our bodies build a tolerance to gabapentin. So start with the lowest dose possible and when that dose eventually stops working, increase it only as much as you have to. I have been on 100 mg of gabapentin (and also take THC) for what felt like a long time. I think I’m finally at the point where I will need to increase it.