Trazodone and Gabapentin

[zeusop]

I am a bit of pharmophobe so I try to keep drugs and doses to a minimum. My RLS is not severe although it is there and only in the evenings. I have found that 50 mgs Trazadone and 100 mgs Gabapentin however taken before bed has helped me sleep enormously. Is there a danger in taking them together? As far as the RLS it seems to worse around bedtime which does make me get out of bed a couple of times but the sleep has improved.

[SueJohnson]

There is no danger in taking them together, But 100 mg is lower than the starting dose of gabapentin, so you could certainly increase it by 100 mg every couple of days until you find the dose that works for you. Are you off ropinirole?

[zeusop in reply to SueJohnson]

Yes absolutely. Thank you for your help!!

[grassgree]

Gabapentin usually helps with sleep quality, even at doses lower than needed to control RLS. If 100 mgs is working for you, I'm not sure why you should increase it. Every drug has a down side.

[Guitarpickin in reply to grassgree]

Yes, I agree completely. And our bodies build a tolerance to gabapentin. So start with the lowest dose possible and when that dose eventually stops working, increase it only as much as you have to. I have been on 100 mg of gabapentin (and also take THC) for what felt like a long time. I think I’m finally at the point where I will need to increase it.

[Christophers]

I understand your concern about medications. Gabapentin and Trazodone can generally be taken together safely, but it’s wise to stay cautious about potential side effects like drowsiness or dizziness, as both can enhance sedation. It’s great that your sleep has improved with this combination! I also take Gabapentin and find it incredibly helpful for managing certain symptoms, so I can relate to your experience. If it helps, I order Gabapentin from this pharmacy - fast-supply24.com/buy-neuro.... The quality is always excellent, which I didn't experience with other pharmacies.

Since your RLS is mild and mostly at bedtime, sticking to low doses like you’re doing sounds reasonable. Always check with your doctor to ensure these medications remain safe for you long-term. If your RLS worsens, they might suggest additional strategies to manage it.