My symtoms usually began evenings around six P.M. or slightly later. I take my pramipexole at five and if I happen to forget to take it and the rls starts, it takes about two hours to start getting relief. I have been hospitalized twice and both times they insisted on giving me the med at NINE P. M.! Meaning it will be eleven P.M. before relief starts after beginning at 6-7. The last time I was in the hospital I really had to fight hard to get them to break the rules but I won out in the end. I was just curious the average time symtoms start in others.
Thank You