Horizitom: Transitioning off of... - Restless Legs Syn...

Restless Legs Syndrome

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Horizitom

tuckerdog109 profile image
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Transitioning off of Pramipexole and onto Horiziton/Gabapentin. 600 no of Gabapentin and results have been so so. Take it a 5 pm and ot seems I start getting the symptoms a bit and other nights not. Taking 12.5 mg Ambien trying to sleep and last night was not good. Buzzing toes , fingers and extremities were going crazy. Finally at 2:30’this morning I took a half a thc gummie and slept till 8 am. Was shocked I slept so long and I have no symptoms this morning. But, my wife is aggravated with me saying the mix was dangerous Other than that, it’s a good start of the day. Going to ask mid I can boost the Gabapentin to 8-1200 mg. I notice since coming off the Prami, I don’t have to stop driving to take a 15 minute nap nor am I startled out of a semi trance while driving.

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SueJohnson profile image
SueJohnson

Which gabapentin or Horizant? I assume you meant only gabapentin?

How long have you been off pramipexole If the symptoms haven't settled from that gabapentin won't help you much. And it takes 3 weeks for gabapentin to be fully effective. After that increase it by 100 mg every couple of days until you find the dose that works for you. Take it 1-2 hours before bedtime. If you need more than 600 mg take the extra 4 hours before bedtime as it is not as well absorbed above 600 mg. If you need more than 1200 mg, take the extra 6 hours before bedtime. Most of the side effects of gabapentin or pregabalin will disappear after a few weeks and the few that don't will usually lessen. Those that remain are usually worth it for the elimination of the RLS symptoms. If you take magnesium even in a multivitamin, take it at least 3 hours before or after taking gabapentin as it will interfere with the absorption of gabapentin and if you take calcium don't take it within 2 hours for the same reason (not sure about pregabalin). According to the Mayo Clinic Updated Algorithm on RLS: "Most RLS patients require 1200 to 1800 mg of gabapentin ."

I assume you also meant CBD or THC gummies. They are OK to take with gabapentin.

Have you had your ferritin checked? If so what was it?

tuckerdog109 profile image
tuckerdog109 in reply toSueJohnson

No ferritin check as of date. Thanks for your insight

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