I have recommended using small doses of Paracetamol/Acetominophen to potentiate an opioid if it is being compromised by a trigger.
This works well. However-- I have a cautionary tale to relate.
I had a few molar tooth extractions recently and took extra paracetamol to relieve the pain. It certainly achieved that, but when I stopped taking it ,I experienced horrible withdrawals for about 4 days and nights.
And nowhere to go- I couldn't take more paracetamol, so just tapered it down over another four or five days and endured the torture.
I'm not sure what the alternives are for extra pain relief while on opioids, that don't cause more problems.
Just passing on my personal experience.