Valdoxan and RLS: anyone here have ex... - Restless Legs Syn...

Restless Legs Syndrome

22,319 members16,384 posts

Valdoxan and RLS: anyone here have experience with this antidepressant

Runninglegs2 profile image
2 Replies

My Dr is talking about me trying Valdoxan (Agomelatine) for depression. Apparently it works on the melatonin pathway not the serotonin pathways and so he says it shouldn’t aggravate restless legs.

Has anyone here tried it before and if so what was your experience with it.

I know some people say Melatonin aggravates their legs.

Much appreciated.

Written by
Runninglegs2 profile image
Runninglegs2
To view profiles and participate in discussions please or .
Read more about...
2 Replies
SueJohnson profile image
SueJohnson

An article in my research say it is OK. Some say not. Only way to know is to try it.

Runninglegs2 profile image
Runninglegs2 in reply toSueJohnson

thanks Sue for your reply. I’ll try them and see what happens.

Not what you're looking for?

You may also like...

My experience with RLS

Hi I am new to this community. I have suffered with RLS for many years. Not sleeping well because...

Anyone experience RLS with Sucralose (Splenda) Sweeteners?

I have intermittent restless leg problems. Late at night I get a 'pressure' in my legs and it's...
Chancery profile image

My experience with RLS

Hello, I have suffered from RLS since I was a child. I always used to explain to my mum how I...
tom456 profile image

Sorbolene Lotion experience and my RLS

I was prescribed Sorbolene Lotion for my lower legs for dry skin - had very bad dry skin that was...
bernardnz profile image

Anyone have experience on how psilocybin may effect RLS

I'm looking to give psilocybin a try for my treatment resistant depression. My big concern is that...
ziggypiggy profile image

Moderation team

Kaarina profile image
KaarinaAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.