Lyrica/Pregabalin side effects - Restless Legs Syn...

Restless Legs Syndrome

22,314 members16,370 posts

Lyrica/Pregabalin side effects

charlie1234567890 profile image

I am currently taking Lyrica/pregabalin with side effects of fatigue, clumsiness and eye twitching. Has anyone had these side effects subside with time? I've been taking it for about a month now. It seems to work fairly well but not sure I can handle the side effects. I'm only on 25mg.

Written by
charlie1234567890 profile image
charlie1234567890
To view profiles and participate in discussions please or .
Read more about...
8 Replies
BAK524 profile image
BAK524

I was up to 150mg and had every side effect on the books. Constant fatigue, muscle twitches, loss of fine motor abilities, brain fog, difficulty walking, difficulty finishing sentences, tinnitus, constipation. Eventually I started having bad bouts of anxiety. The real problems started when I tried to taper off. I did so very slowly, but it was still hell. Bad insomnia, panic anxiety, increases in RLS. It took me 8 months to get off. I'm now 5 days pregabalin free. It's the worst medication I've ever been on in my life. People really react differently to this stuff, and most seem to get through the side effects with time. I recommend you proceed slowly and with caution. 25 mgs is considered a low dose, but you may find some benefit.

charlie1234567890 profile image
charlie1234567890 in reply toBAK524

Thank you for your response. I figured it wasn't a good drug when they list 90 different side effects. I'm running out of options.

Munroist profile image
Munroist

Lots of people benefit from it without the side effects, me being one. I'm not sure whether it made my tinnitus worse but it was definitely there before. I got to 300mg without anything too worrying. The doctors advised me not to look at the side effect list ...

SueJohnson profile image
SueJohnson

You might want to try switching to gabapentin. Although they are basically the same drug except on pregabalin you don't need to divide the doses, and the side effects are basically the same, some people find that the side effects that bother them on one don't bother them on the other. Multiple the lyrica amount by 6 to get the correct dose so 25 time 6 would be 150 mg of gabapentin.

charlie1234567890 profile image
charlie1234567890 in reply toSueJohnson

I've tried gabapentin. It made me so dizzy I couldn't walk.

march1044 profile image
march1044

Lyrica and gabapentin also can cause a weight gain, since they increase your appetite.

Pam34 profile image
Pam34

I’ve been on 150mg of Pregabalin for several years. Side effects tended to settle and lessen after a few weeks and those I’m left with are more than worth it for a good nights sleep. All drugs have side effects and most disappear after time. It’s up to you whether you think they outweigh the benefits of a good night sleep. For me there was no contest.

It sounds like you're experiencing substantial side effects for such a low dose. Are you taking it at night or in the daytime?

I'm on 300mg and do have side effects - daytime fatigue, reduced cognitive functioning, slight dulling of feelings. And a few hours after taking it, i do feel a bit drunk. Despite all this, it works in the main.

The side effects do subside with time, but don't necessarily go away.

If it's really impacting you, eg your ability to to drive etc I'd be discussing this with your doctor.

Not what you're looking for?

You may also like...

Lyrica side effects

I have been on Lyrica for about five weeks now and am getting almost 100% relief of my RLS. The...
LanaCSR profile image

Pregabalin side effects

My mum was taking pregabalin 75mg (twice a day)with no side effects, however it wasn't helping her...
Bejwo50 profile image

Pregabalin - side effects/ what next

hi all I’m on 75 mg of Pregabalin - stable dose for 5-6 weeks . Side effects of nausea ,...
LFIT profile image

Lyrica ocular side effects and more

I am an optometrist in Colorado with severe RLS symptoms. This forum is an excellent method of...
WelbyB profile image

Pregabalin side-effects? Or something else?

Dear fellow sufferers I wonder if I could get your advice and feedback on side affects I appear to...
Rachelp1 profile image

Moderation team

Kaarina profile image
KaarinaAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.