Oxycodone

Hello!

I have been taking oxycodone for RLS since October last year.

It has helped me a lot. However, the nausea is still ongoing and by 5pm in the evening I feel restless and unwell with the sicky feeling.

I'm wondering if this could be withdrawal from the med before I take my next dose?

I take 10mg at bedtime.

Any thoughts?

[Madlegs1]

If it's the longacting OXY such as Oxycontin, then it only lasts for about 9 to 12 hours. Many people will experience mild withdrawal from it if you only take it once a day.You could try Oxycontin 5 for the other half of the 24 hours, but in my case that wasn't enough. I had to go with the 10 dose twice a day ,to provide a continuous opioid cover.

If you are in an area that will prescribe methadone, then that might be a better option, as it lasts a lot longer.

Good luck.

[Hidden in reply to Madlegs1]

Thankyou so much!I'm on 10mg slow release as the 5mg wasn't enough.

I'm in London and have consulted Prof Walker who was great. I will mention 10x2.

I really appreciate your help.

[Joolsg in reply to Hidden]

Oxycontin ( and Targinact) are supposed to be given twice a day to avoid mini withdrawals. Look up the NICE guidelines on Targinact.

nice.org.uk/advice/esnm67/c...

I agree with others. Consider 5mg twice a day or even 3 times a day - every 8 hours.

For the nausea, I found medical cannabis oil really helpful. It's now legal in the UK & available through Project-twenty21.

drugscience.org.uk/project-...

[Hidden in reply to Joolsg]

I appreciate your answer. Thank you so much

[ziggypiggy in reply to Madlegs1]

I too had to go from one 15mg oxy to twice daily as coverage wasnt enough. Lucky to get 8 hours out of one dose. I didn't experience nausea on one dose but definitely was restless trying to time when to take the one dose based on my nightly activities and my previous nights sleep. Two doses relieved most of that worry.

[Hidden in reply to ziggypiggy]

Thanks so much! Really helpful.

[Beckonwood]

I take oxycodone 5 mg and cut the pills in half. I start taking the pills at 5pm and every hour I take a half until eleven o clock. I find they usually work every once in awhile I will wake at 2 or 3 am and at times will have RLS symptoms so then i take another half a pill. I was on mirapex for years and had to go cold turkey to get off. It was awful.

[Hidden in reply to Beckonwood]

Many thanks!