I have read some of your posts about Lyrica and am not feeling very positive about trying it. My neurologist suggested it since I’m to not able to tolerate pramipexole and sinemet. I need some feedback. One of the side effects I’ve had from DAs is extreme depression/anxiety. I am at the end of my rope. My inclination is that low dose opioids might be the answer but we all know how most doctors feel about prescribing opioids.