I have suffered from RLS long enough. I would lye I bed hurting , hitting my legs, putting them on heating pad, massager , icy hot,, i have Taken pregablin, duloxetine, gabapentin.I took ropinirole,which was working for a about 6 months.i have had MRI on head and back. Circulation test. And other testing. Blood work etc. Always seemed like my doctor was just thinking I was exaggerating the pain . I'm turning 50 never used drugs , was always against it. Long story short. Cannabis is working for me.. Cannabis oil is more effective. It's legal here and I was able to get it prescribed and it's life changing. Take it for what it's worth. The pain was very painful for me!! I sleep at night now..