My husband (we are in US) who is 74 has had RLS since a child. He's tried everything and has been on Ropinerole for the past ten years or so. He has a lot of trouble with it as it makes him very, very nauseous even with food in his stomach. He was on 4 mg but upped it to 6 mg a couple months ago when it started happening earlier in the evening. (used to be 9PM or so) and now it can start as early as 6 or 7P, yesterday 4P. On several occasions--he missed the med, it was withheld at the hospital, he couldn't keep it down-- he leg movements are so strong it looks like convulsions and then it progresses to him losing all muscle tone in his body, very scary, he just goes limp and can't move.
He regular iron tests are normal and he won't supplement because "it's dangerous for the elderly to take extra iron, esp men." He hasn't found a doc who knows much or can be helpful. About 10 yrs ago where we used to live he found a neurologist who said, if necessary, he could go up to 8 mg per day.
Suggestions welcome. Questions:
1)do others have GI problems/nausea with Ropinerole? Has anyone every heard of having it compounded into a suppository?
2)The only thing that's changed in the last month or so is that he has doubled his dose of Pantoprazole, a proton pump inhibitor, and I read that might possible inhibit uptake of iron?
We're at a loss to figure the next step and it's pretty scary. Thanks.