I have had RLS since my twenties. In my 40's it got to the point it was waking me up at nights and it was in my shoulders as well as legs. I was given Ropinirole, that helped at first with 1 mg, but I found I had to keep increasing the dosage and then found out the effects it had. I tried one day to stop cold turkey, not a good idea as it was the worst 48 hours of my life. Now I know how addicts feel when they withdraw. I found the UK supplement Quiet Legs and that has gotten me down to half the dosage I was using. In the meantime, I've also upped my Magnesium, use infrared lights on my back and shoulders (this truly helped to lesson the time and severity of the bouts of RLS). I also have had some Cranial-Sacrum work and that helped to relieve the symptoms and I had some truly restful couple of days after. I had gone to Mayo Clinic and all they said was this starts in the ganglia of the brain, where Parkinson's originates, but you won't get Parkinson's and if you get 75% relief from the medication that is all they hope for. As well as the supplements and treatments I try to be sure I get plenty of rest as when I'm tired its the worst or when I'm ill.