Does anyone remember anything specific about what may have ignited your first episode of RLS? I think that some medI cation may have had something to do with my first episodes of RLS. It started with a horrible pain in the instep of my right foot. It burned, and pulled. I thought that I was having another episode of plan t AR fascitis, which I had suffered some years back. That condition had been helped by a shot in the foot and the purchase of some Birkenstock sandals which really helped and which I virtually wear all of the time.