NIPS-led researchers measured the heightened pain response when mice with a leg nerve injury were poked on the underside of a hind paw with a fine filament. Simultaneous live imaging of calcium ions in the brain's S1 cortex showed that certain signaling pathways were activated in astrocytes, a type of cell that helps neurons. Certain signaling pathways in S1 astrocytes were activated and triggered S1 cortex rewiring, contributing to mechanical hypersensitivity (allodynia). Such astrocyte-mediated changes in the brain may provide new clues for novel therapeutic strategies for treating debilitating mechanical allodynia
Pain "main switch": NIPS-led researchers... - Ramsays Disease
Pain "main switch"
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bulletheblue
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Something better for the pain would certainly be welcome.
Glial cell inflammation appears as though it's gaining greater acceptance amongst researchers in this field.
Much improved upon the view taken by NIH Dr Walitt's "pain and related interoceptive disorders" as "social construction of illness and disease."
Hurry up finding pain off switch pleeeaaaaaase