I'm wondering if PSP has an effect on sex life. My wife and I were happily having sex until about one or two years into PSP. Suddenly she said she no longer wanted to do it. I'm wondering if the PSP has affected the nerves in that area of her body or if it is just a mental thing. I know it isn't depression or due to her outlook since diagnosis because those things are fine and havent changed. Maybe some women in the group have some insight into this. Also curious is this happens to men who have PSP (diminished appitite for sex). thanks in advance for your input.