What causes fatigue and tiredness. Does anyone know please ?
CBD Tiredness: What causes fatigue and... - PSP Association
CBD Tiredness
The brain is working overtime for the parts that have stopped functioning. It’s using lots of energy to do so.
Thanks Jeff I thought along those lines...
Like Jeff166 said the brain is working hard to compensate for the areas that aren't functioning correctly. The body is also working harder to do normal things. Right before Dad stopped walking his O/T said he was probably expending as much energy walking 10 feet as a healthy person would running a 50 yard dash.
Ron
Agree with both these comments. I also find Mum sometimes sitting in her chair with her legs out in front of her, looking quite normal until you look closely and her feet aren't touching the floor but hovering about half an inch above, think how much effort that takes!
Hi Northstar
This was posted some six years ago, "There is strong evidence that the condition of chronic fatigue syndrome is connected with mitochondrial dysfunction, and this may explain much of the tiredness in PSP."
That same mitochondrial dysfunction causes weight loss later in the illness.
Mitochondria exist in every cell in the body. A key function they perform is releasing sugars to the cell so that it can perform. If they don't release sugars sufficiently tiredness can be result.
I believe things have moved on a bit and now it is thought that the mitochondrial dysfunction is, to some degree, caused by a problem with a metabolic pathway in the brain. In plain language some of the brain chemistry becomes faulty.
Someone else my be aware of more recent research than I.
I often go to websites for Parkinson's which has some cross over with the PSP/CBD family of illnesses and much more work has been done in that area.
One article I read there makes the following points:
Depression or low mood increases the fatigue and medication for depression can help in those cases.
Exercise can also lessen the sense of fatigue over time.
Disturbed sleep can increase the fatigue and again medication can help in those cases.
I do hope this helps a little.
Great answers were from everyone but I think that some of the medication can also cause tiredness
Dx
When my wife was initially diagnosed with CBD she was taken into hospital with a bladder infection and she was suffering hallucinations and other dementia symptoms. I said to the hospital chaplain how strange it was that the bladder should have such an influence on the brain. He politely pointed out to me that it was due to the brain working overtime in fighting the infection. I think that provides an answer to a large number of posts I have just read this morning. I'm on a respite break so have only just had my breakfast at mid day.